(R)-3-cyclopentyl-2-((N-((4-methoxybenzyl)oxy)formamido)methyl)propanoic acid

Base Information

Chemical Name:(R)-3-cyclopentyl-2-((N-((4-methoxybenzyl)oxy)formamido)methyl)propanoic acid
CAS No.:1268819-51-7
Molecular Formula:C₁₈H₂₅NO₅
Molecular Weight:335.4
Hs Code.:

Synonyms:(R)-3-cyclopentyl-2-((N-((4-methoxybenzyl)oxy)formamido)methyl)propanoic acid

Suppliers and Price of (R)-3-cyclopentyl-2-((N-((4-methoxybenzyl)oxy)formamido)methyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-3-cyclopentyl-2-((N-((4-methoxybenzyl)oxy)formamido)methyl)propanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-3-cyclopentyl-2-((N-((4-methoxybenzyl)oxy)formamido)methyl)propanoic acid

There total 8 articles about (R)-3-cyclopentyl-2-((N-((4-methoxybenzyl)oxy)formamido)methyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₇H₂₅NO₄

: 109-94-4
formic acid ethyl ester

: 1268819-51-7
(R)-3-cyclopentyl-2-((N-((4-methoxybenzyl)oxy)formamido)methyl)propanoic acid

Guidance literature:: at 20 - 60 ℃;
DOI:10.1016/j.ejmech.2014.07.106

Reference yield:

: 5499-96-7
diethyl 2-(cyclopentylmethyl)malonate

: 1268819-51-7
(R)-3-cyclopentyl-2-((N-((4-methoxybenzyl)oxy)formamido)methyl)propanoic acid

Guidance literature:: Multi-step reaction with 7 steps

1.1: sodium hydroxide / water / 4 h / 20 °C / Reflux

2.1: diethylamine; formaldehyd / ethanol / Reflux

3.1: triethylamine / tetrahydrofuran / -78 - 20 °C / Inert atmosphere

4.1: n-butyllithium / tetrahydrofuran / -78 - 20 °C / Inert atmosphere

4.2: -78 - 20 °C / Inert atmosphere

5.1: 24 h / 45 °C / Inert atmosphere

5.2: 1.5 h / Inert atmosphere

5.3: 0.5 h / Inert atmosphere

6.1: dihydrogen peroxide; lithium hydroxide monohydrate / water; tetrahydrofuran / 1 h / 0 °C

7.1: 20 - 60 °C

With n-butyllithium; formaldehyd; lithium hydroxide monohydrate; dihydrogen peroxide; diethylamine; triethylamine; sodium hydroxide; In tetrahydrofuran; ethanol; water;
DOI:10.1016/j.ejmech.2014.07.106

Reference yield:

: 5243-36-7
2-cyclopentylmethyl-malonic acid

: 1268819-51-7
(R)-3-cyclopentyl-2-((N-((4-methoxybenzyl)oxy)formamido)methyl)propanoic acid

Guidance literature:: Multi-step reaction with 6 steps

1.1: diethylamine; formaldehyd / ethanol / Reflux

2.1: triethylamine / tetrahydrofuran / -78 - 20 °C / Inert atmosphere

3.1: n-butyllithium / tetrahydrofuran / -78 - 20 °C / Inert atmosphere

3.2: -78 - 20 °C / Inert atmosphere

4.1: 24 h / 45 °C / Inert atmosphere

4.2: 1.5 h / Inert atmosphere

4.3: 0.5 h / Inert atmosphere

5.1: dihydrogen peroxide; lithium hydroxide monohydrate / water; tetrahydrofuran / 1 h / 0 °C

6.1: 20 - 60 °C

With n-butyllithium; formaldehyd; lithium hydroxide monohydrate; dihydrogen peroxide; diethylamine; triethylamine; In tetrahydrofuran; ethanol; water;
DOI:10.1016/j.ejmech.2014.07.106