C₃₉H₅₈O₇Si

Base Information

• Chemical Name: C₃₉H₅₈O₇Si
• CAS No.: 1310056-96-2
• Molecular Formula: C₃₉H₅₈O₇Si
• Molecular Weight: 666.971
• Mol file: 1310056-96-2.mol

Synonyms:C₃₉H₅₈O₇Si

Chemical Property of C₃₉H₅₈O₇Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₉H₅₈O₇Si

There total 12 articles about C₃₉H₅₈O₇Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

C25H30O5 (1310056-89-3) + (E,E)-7-(tert-butyldimethylsilanyloxy)-4-methylhepta-2,4-dien-1-ol (717918-91-7) → C39H58O7Si (1310056-96-2)

Guidance literature:

With pyridinium p-toluenesulfonate; In dichloromethane; at 0 - 20 ℃; optical yield given as %de; Inert atmosphere;

DOI:10.3987/COM-10-S(E)93

Reference yield:

2-allyl-1,3-propanediol (42201-43-4) → C39H58O7Si (1310056-96-2)

Guidance literature:

Multi-step reaction with 6 steps

1.1: sodium hydride / tetrahydrofuran; N,N-dimethyl-formamide; mineral oil / 0 - 20 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: potassium osmate(VI) dihydrate; 4-methylmorpholine N-oxide / water; acetone / 12 h / 20 °C / Inert atmosphere

3.1: sodium periodate / tetrahydrofuran; water / 0 - 20 °C / Inert atmosphere

4.1: tert.-butyl lithium / tetrahydrofuran; pentane / -78 - 0 °C / Inert atmosphere

4.2: 1 h / -78 °C / Inert atmosphere

5.1: pyridine; dmap / dichloromethane / 12 h / 20 °C / Inert atmosphere

6.1: pyridinium p-toluenesulfonate / dichloromethane / 0 - 20 °C / Inert atmosphere

With pyridine; dmap; potassium osmate(VI) dihydrate; sodium periodate; tert.-butyl lithium; pyridinium p-toluenesulfonate; sodium hydride; 4-methylmorpholine N-oxide; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetone; mineral oil; pentane;

DOI:10.3987/COM-10-S(E)93

Reference yield:

3-(tert-butyldimethylsilanyloxy)propionaldehyde (89922-82-7) → C39H58O7Si (1310056-96-2)

Guidance literature:

Multi-step reaction with 6 steps

1: toluene / 12 h / Inert atmosphere; Reflux

2: diisobutylaluminium hydride / hexane; dichloromethane / 2 h / -78 °C / Inert atmosphere

3: sulfur trioxide pyridine complex; dimethyl sulfoxide; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

4: toluene / 12 h / Inert atmosphere; Reflux

5: diisobutylaluminium hydride / hexane; dichloromethane / 1 h / -78 °C / Inert atmosphere

6: pyridinium p-toluenesulfonate / dichloromethane / 0 - 20 °C / Inert atmosphere

With sulfur trioxide pyridine complex; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; dimethyl sulfoxide; triethylamine; In hexane; dichloromethane; toluene; 3: Parikh-Doering oxidation / 4: Wittig olefination;

DOI:10.3987/COM-10-S(E)93

upstream raw materials:

C₂₅H₃₀O₅

(E,E)-7-(tert-butyldimethylsilanyloxy)-4-methylhepta-2,4-dien-1-ol

(2-propenyl)propanedioic acid diethyl ester

2-allyl-1,3-propanediol

Downstream raw materials:

4-Benzyloxy-3-benzyloxymethyl-1-{2-[(2E,4E)-7-(tert-butyl-dimethyl-silanyloxy)-4-methyl-hepta-2,4-dienyloxy]-tetrahydro-furan-2-yl}-butan-1-ol

4-Benzyloxy-3-benzyloxymethyl-1-{2-[(2E,4E)-7-(tert-butyl-dimethyl-silanyloxy)-4-methyl-hepta-2,4-dienyloxy]-tetrahydro-furan-2-yl}-butan-1-one