(E)-3-(5-(3,5-bis((1E,3E)-4-(4-(di-p-tolylamino)phenyl)buta-1,3-dienyl)-4-(octyloxy)phenyl)-3-hexylthiophen-2-yl)-2-cyanoacrylic acid

Base Information

Chemical Name:(E)-3-(5-(3,5-bis((1E,3E)-4-(4-(di-p-tolylamino)phenyl)buta-1,3-dienyl)-4-(octyloxy)phenyl)-3-hexylthiophen-2-yl)-2-cyanoacrylic acid
CAS No.:1428113-81-8
Molecular Formula:C₇₆H₇₉N₃O₃S
Molecular Weight:1114.55
Hs Code.:

Synonyms:(E)-3-(5-(3,5-bis((1E,3E)-4-(4-(di-p-tolylamino)phenyl)buta-1,3-dienyl)-4-(octyloxy)phenyl)-3-hexylthiophen-2-yl)-2-cyanoacrylic acid

Suppliers and Price of (E)-3-(5-(3,5-bis((1E,3E)-4-(4-(di-p-tolylamino)phenyl)buta-1,3-dienyl)-4-(octyloxy)phenyl)-3-hexylthiophen-2-yl)-2-cyanoacrylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-3-(5-(3,5-bis((1E,3E)-4-(4-(di-p-tolylamino)phenyl)buta-1,3-dienyl)-4-(octyloxy)phenyl)-3-hexylthiophen-2-yl)-2-cyanoacrylic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-3-(5-(3,5-bis((1E,3E)-4-(4-(di-p-tolylamino)phenyl)buta-1,3-dienyl)-4-(octyloxy)phenyl)-3-hexylthiophen-2-yl)-2-cyanoacrylic acid

There total 4 articles about (E)-3-(5-(3,5-bis((1E,3E)-4-(4-(di-p-tolylamino)phenyl)buta-1,3-dienyl)-4-(octyloxy)phenyl)-3-hexylthiophen-2-yl)-2-cyanoacrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 1428113-78-3
5-(3,5-bis((1E,3E)-4-(4-(di-p-tolylamino)phenyl)buta-1,3-dienyl)-4-(octyloxy)phenyl)-3-hexylthiophene-2-carbaldehyde

: 372-09-8
cyanoacetic acid

: 1428113-81-8
(E)-3-(5-(3,5-bis((1E,3E)-4-(4-(di-p-tolylamino)phenyl)buta-1,3-dienyl)-4-(octyloxy)phenyl)-3-hexylthiophen-2-yl)-2-cyanoacrylic acid

Guidance literature:: With piperidine; In chloroform; acetonitrile; at 80 ℃; for 12h; Inert atmosphere;
DOI:10.1016/j.dyepig.2013.01.009

Reference yield:

: 925452-57-9
(E)-3-(4-(di-p-tolylamino)phenyl)acrylaldehyde

: 1428113-81-8
(E)-3-(5-(3,5-bis((1E,3E)-4-(4-(di-p-tolylamino)phenyl)buta-1,3-dienyl)-4-(octyloxy)phenyl)-3-hexylthiophen-2-yl)-2-cyanoacrylic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium tert-butylate / tetrahydrofuran / 17 h / 20 - 45 °C / Inert atmosphere

2.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 30 h / 100 °C / Inert atmosphere

2.2: 0.5 h / 20 °C

3.1: piperidine / chloroform; acetonitrile / 12 h / 80 °C / Inert atmosphere

With piperidine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium tert-butylate; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide; acetonitrile; 1.1: |Wittig-Horner Reaction / 2.1: |Stille Cross Coupling / 3.1: |Knoevenagel Condensation;
DOI:10.1016/j.dyepig.2013.01.009

Reference yield:

: 42906-19-4
4-[N,N-di(p-tolyl)amino]benzaldehyde

: 1428113-81-8
(E)-3-(5-(3,5-bis((1E,3E)-4-(4-(di-p-tolylamino)phenyl)buta-1,3-dienyl)-4-(octyloxy)phenyl)-3-hexylthiophen-2-yl)-2-cyanoacrylic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: potassium tert-butylate / N,N-dimethyl-formamide / 17 h / 20 - 50 °C / Inert atmosphere

2.1: trichlorophosphate / 24 h / 60 °C

3.1: potassium tert-butylate / tetrahydrofuran / 17 h / 20 - 45 °C / Inert atmosphere

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl-formamide / 30 h / 100 °C / Inert atmosphere

4.2: 0.5 h / 20 °C

5.1: piperidine / chloroform; acetonitrile / 12 h / 80 °C / Inert atmosphere

With piperidine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium tert-butylate; trichlorophosphate; In tetrahydrofuran; chloroform; N,N-dimethyl-formamide; acetonitrile; 1.1: |Wittig Olefination / 2.1: |Vilsmeier-Haack Formylation / 3.1: |Wittig-Horner Reaction / 4.1: |Stille Cross Coupling / 5.1: |Knoevenagel Condensation;
DOI:10.1016/j.dyepig.2013.01.009