Acetamide, 2-(acetylamino)-N-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N-methyl-

Base Information

Chemical Name:Acetamide, 2-(acetylamino)-N-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N-methyl-
CAS No.:65808-66-4
Molecular Formula:C18H16Cl2N2O3
Molecular Weight:379.24
Hs Code.:2924299090
DSSTox Substance ID:DTXSID40215994
Wikidata:Q83092117
ChEMBL ID:CHEMBL420803
Mol file:65808-66-4.mol

Synonyms:65808-66-4;BRN 5134242;Acetamide, 2-(acetylamino)-N-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N-methyl-;4-Chloro-2-(o-chlorobenzoyl)-N-methyl-N(sup alpha)-acetylglycinanilide;2-(Acetylamino)-N-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N-methylacetamide;C18H16Cl2N2O3;CHEMBL420803;DTXSID40215994;2-ACETAMIDO-N-[4-CHLORO-2-(2-CHLOROBENZOYL)PHENYL]-N-METHYL-ACETAMIDE;LS-7945

Suppliers and Price of Acetamide, 2-(acetylamino)-N-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Acetamide, 2-(acetylamino)-N-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N-methyl-

Chemical Property:

Vapor Pressure:7.33E-16mmHg at 25°C
Boiling Point:631.6°C at 760 mmHg
Flash Point:335.8°C
PSA：69.97000
Density:1.344g/cm³
LogP:4.16360
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:378.0537978
Heavy Atom Count:25
Complexity:515

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)NCC(=O)N(C)C1=C(C=C(C=C1)Cl)C(=O)C2=CC=CC=C2Cl

Technology Process of Acetamide, 2-(acetylamino)-N-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N-methyl-

There total 4 articles about Acetamide, 2-(acetylamino)-N-(4-chloro-2-(2-chlorobenzoyl)phenyl)-N-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.5%

: 76337-78-5
4-chloro-2-(o-chloro-2-hydroxybenzyl)-N-methyl-N^α-acetylglycinanilide

: 65808-66-4
4-chloro-2-(o-chlorobenzoyl)-N-methyl-N^α-acetylglycinanilide

Guidance literature:: With jones reagent; In acetone; at 0 ℃;
DOI:10.1021/jm00133a006

Reference yield: 47.4%

: 59180-41-5
4-chloro-2-(o-chlorobenzoyl)-N-methyl-N^α-glycinanilide hydrobromide

: 75-36-5
acetyl chloride

: 65808-66-4
4-chloro-2-(o-chlorobenzoyl)-N-methyl-N^α-acetylglycinanilide

Guidance literature:: In N,N-dimethyl-formamide; for 3.5h; Ambient temperature;
DOI:10.1021/jm00133a006

Reference yield:

: 59180-29-9
2-methylamino-5,2'-dichlorobenzhydrol

: 65808-66-4
4-chloro-2-(o-chlorobenzoyl)-N-methyl-N^α-acetylglycinanilide

Guidance literature:: Multi-step reaction with 2 steps

1: hexamethylphosphoric acid triamide; acetonitrile / Ambient temperature

2: 66.5 percent / Jones reagent / acetone / 0 °C

With jones reagent; In N,N,N,N,N,N-hexamethylphosphoric triamide; acetone; acetonitrile;
DOI:10.1021/jm00133a006