dimethyl 2-(furan-2-yl)-2-phenylcyclopropane-1,1-dicarboxylate

Base Information

• Chemical Name: dimethyl 2-(furan-2-yl)-2-phenylcyclopropane-1,1-dicarboxylate
• CAS No.: 1443753-19-2
• Molecular Formula: C₁₇H₁₆O₅
• Molecular Weight: 300.311
• Mol file: 1443753-19-2.mol

Synonyms:dimethyl 2-(furan-2-yl)-2-phenylcyclopropane-1,1-dicarboxylate

Chemical Property of dimethyl 2-(furan-2-yl)-2-phenylcyclopropane-1,1-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of dimethyl 2-(furan-2-yl)-2-phenylcyclopropane-1,1-dicarboxylate

There total 1 articles about dimethyl 2-(furan-2-yl)-2-phenylcyclopropane-1,1-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

1-(2-furyl)-1-phenylethylene (75488-41-4) + bis(methoxycarbonyl)(phenyliodinio)methanide (145838-86-4) → dimethyl 2-(furan-2-yl)-2-phenylcyclopropane-1,1-dicarboxylate (1443753-19-2)

Guidance literature:

With bis{rhodium[3,3'-(1,3-phenylene)bis(2,2-dimethylpropanoic acid)]}; In neat (no solvent); at 23 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ol401248p

Reference yield: 97.0%

dimethyl 2-(furan-2-yl)-2-phenylcyclopropane-1,1-dicarboxylate (1443753-19-2) + (2-aminophenyl)(phenyl)methanone (2835-77-0) → dimethyl 2-(((1R,2R)-2-((2-benzoylphenyl)amino)-5-oxo-1-phenylcyclopent-3-en-1-yl)methyl)malonate

Guidance literature:

With 1,1,1-trifluoro-N-((2r)-4-oxido-2,6-bis(2,4,6-triisopropylphenyl)-8,9,10,11,12,13,14,15-octahydrodinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)methanesulfonamide; scandium tris(trifluoromethanesulfonate); In tetrahydrofuran; chloroform; at -10 ℃; for 17h; stereoselective reaction; Inert atmosphere;

DOI:10.1021/acs.orglett.0c03413

Reference yield: 95.0%

dimethyl 2-(furan-2-yl)-2-phenylcyclopropane-1,1-dicarboxylate (1443753-19-2) + o-chloroaniline (95-51-2) → dimethyl 2-((2-((2-chlorophenyl)amino)-5-oxo-1-phenylcyclopent-3-en-1-yl)methyl)malonate

Guidance literature:

With scandium tris(trifluoromethanesulfonate); In tetrahydrofuran; chloroform; at 23 ℃; for 2h; Temperature; stereoselective reaction; Inert atmosphere;

DOI:10.1021/acs.orglett.0c03413

upstream raw materials:

1-(2-furyl)-1-phenylethylene

bis(methoxycarbonyl)(phenyliodinio)methanide