N-(benzyloxycarbonyl)-L-isoleucyl-1-amino-N-methylcyclopentancarboxanilid

Base Information

Chemical Name:N-(benzyloxycarbonyl)-L-isoleucyl-1-amino-N-methylcyclopentancarboxanilid
CAS No.:116159-78-5
Molecular Formula:C₂₇H₃₅N₃O₄
Molecular Weight:465.593
Hs Code.:

Synonyms:N-(benzyloxycarbonyl)-L-isoleucyl-1-amino-N-methylcyclopentancarboxanilid

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Chemical Property of N-(benzyloxycarbonyl)-L-isoleucyl-1-amino-N-methylcyclopentancarboxanilid

Chemical Property:

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Technology Process of N-(benzyloxycarbonyl)-L-isoleucyl-1-amino-N-methylcyclopentancarboxanilid

There total 3 articles about N-(benzyloxycarbonyl)-L-isoleucyl-1-amino-N-methylcyclopentancarboxanilid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 3160-59-6
N-Cbz-L-Isoleucine

: 116139-91-4
N-methyl-N-phenyl-1-azaspiro[2.4]hept-1-en-2-amine

: 116159-78-5
N-(benzyloxycarbonyl)-L-isoleucyl-1-amino-N-methylcyclopentancarboxanilid

Guidance literature:: In diethyl ether; for 0.5h; Ambient temperature;
DOI:10.1002/hlca.19880710118

Reference yield:

: 73-32-5,959215-79-3,18875-42-8
L-isoleucine

: 116159-78-5
N-(benzyloxycarbonyl)-L-isoleucyl-1-amino-N-methylcyclopentancarboxanilid

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / 2N NaOH / dioxane; toluene / 0 °C

2: 100 percent / diethyl ether / 0.5 h / Ambient temperature

With sodium hydroxide; In 1,4-dioxane; diethyl ether; toluene;
DOI:10.1002/hlca.19880710118

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 116159-78-5
N-(benzyloxycarbonyl)-L-isoleucyl-1-amino-N-methylcyclopentancarboxanilid

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / 2N NaOH / dioxane; toluene / 0 °C

2: 100 percent / diethyl ether / 0.5 h / Ambient temperature

With sodium hydroxide; In 1,4-dioxane; diethyl ether; toluene;
DOI:10.1002/hlca.19880710118