2-((4-(diethylamino)-2-hydroxybenzylidene)amino)-3',6'-bis(ethylamino)-2',7'-dimethylspiro[isoindoline-1,9'-xanthen]-3-one

Base Information

• Chemical Name: 2-((4-(diethylamino)-2-hydroxybenzylidene)amino)-3',6'-bis(ethylamino)-2',7'-dimethylspiro[isoindoline-1,9'-xanthen]-3-one
• CAS No.: 1341198-49-9
• Molecular Formula: C₃₇H₄₁N₅O₃
• Molecular Weight: 603.764
• Mol file: 1341198-49-9.mol

Synonyms:2-((4-(diethylamino)-2-hydroxybenzylidene)amino)-3',6'-bis(ethylamino)-2',7'-dimethylspiro[isoindoline-1,9'-xanthen]-3-one

Chemical Property of 2-((4-(diethylamino)-2-hydroxybenzylidene)amino)-3',6'-bis(ethylamino)-2',7'-dimethylspiro[isoindoline-1,9'-xanthen]-3-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-((4-(diethylamino)-2-hydroxybenzylidene)amino)-3',6'-bis(ethylamino)-2',7'-dimethylspiro[isoindoline-1,9'-xanthen]-3-one

There total 2 articles about 2-((4-(diethylamino)-2-hydroxybenzylidene)amino)-3',6'-bis(ethylamino)-2',7'-dimethylspiro[isoindoline-1,9'-xanthen]-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

rhodamine hydrazide (932013-08-6) + 4-(Diethylamino)salicylaldehyde (17754-90-4) → 2-((4-(diethylamino)-2-hydroxybenzylidene)amino)-3',6'-bis(ethylamino)-2',7'-dimethylspiro[isoindoline-1,9'-xanthen]-3-one (1341198-49-9)

Guidance literature:

With acetic acid; In methanol; dichloromethane; for 20h; Reflux;

DOI:10.1007/s10895-012-1040-6

Reference yield:

rhodamine 19 (41382-37-0) → 2-((4-(diethylamino)-2-hydroxybenzylidene)amino)-3',6'-bis(ethylamino)-2',7'-dimethylspiro[isoindoline-1,9'-xanthen]-3-one (1341198-49-9)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 6 h / Reflux

2: methanol / 6 h / Reflux

With hydrazine hydrate; In methanol; ethanol;

DOI:10.1039/d0cc03985c

upstream raw materials:

rhodamine hydrazide

4-(Diethylamino)salicylaldehyde

rhodamine 19