Prolyl-beta-naphthylamide

Base Information

Chemical Name:Prolyl-beta-naphthylamide
CAS No.:16037-15-3
Molecular Formula:C₁₅H₁₆N₂O
Molecular Weight:240.305
Hs Code.:
DSSTox Substance ID:DTXSID90936283
Nikkaji Number:J354.048K
Wikidata:Q27162618
ChEMBL ID:CHEMBL4062437
Mol file:16037-15-3.mol

Synonyms:prolyl-2-naphthylamide;prolyl-beta-naphthylamide

Suppliers and Price of Prolyl-beta-naphthylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
L-PROLINE BETA-NAPHTHYLAMIDE HYDROCHLORIDE 95.00%
1G
$ 695.00

American Custom Chemicals Corporation
L-PROLINE BETA-NAPHTHYLAMIDE HYDROCHLORIDE 95.00%
100MG
$ 580.55

Total 2 raw suppliers

Chemical Property of Prolyl-beta-naphthylamide

Chemical Property:

Vapor Pressure:6.73E-10mmHg at 25°C
Boiling Point:493.9°Cat760mmHg
PKA:14.27±0.20(Predicted)
Flash Point:203.6°C
PSA：41.13000
Density:1.216g/cm³
LogP:3.73410
Storage Temp.:−20°C
Solubility.:50% aqueous acetic acid: 50 mg/mL, clear, slightly yellow
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:240.126263138
Heavy Atom Count:18
Complexity:305

Purity/Quality:

95% ^*data from raw suppliers

L-PROLINE BETA-NAPHTHYLAMIDE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 45
Safety Statements: 53-45-24/25-22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(NC1)C(=O)NC2=CC3=CC=CC=C3C=C2
Isomeric SMILES:C1C[C@H](NC1)C(=O)NC2=CC3=CC=CC=C3C=C2

Technology Process of Prolyl-beta-naphthylamide

There total 4 articles about Prolyl-beta-naphthylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 169969-06-6
C₂₀H₂₄N₂O₃

: 16037-15-3,16037-21-1
(S)-N-(naphthalen-2-yl)pyrrolidine-2-carboxamide

Guidance literature:: With hydrogenchloride; In ethyl acetate; at 20 ℃;
DOI:10.1002/chem.201003105

Reference yield:

: 15761-39-4,59433-50-0
1-(tert-butoxycarbonyl)-L-proline

: 16037-15-3,16037-21-1
(S)-N-(naphthalen-2-yl)pyrrolidine-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C

2: hydrogenchloride / ethyl acetate / 20 °C

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; ethyl acetate;
DOI:10.1002/chem.201003105

Reference yield:

: 91-59-8
naphthalen-2-ylamine

: 16037-15-3,16037-21-1
(S)-N-(naphthalen-2-yl)pyrrolidine-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C

2: hydrogenchloride / ethyl acetate / 20 °C

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; ethyl acetate;
DOI:10.1002/chem.201003105