N~2~-(5-Chloro-2-methoxyphenyl)-N~2~-(methanesulfonyl)-N-(2-methoxy-5-methylphenyl)glycinamide

Base Information

Chemical Name:N~2~-(5-Chloro-2-methoxyphenyl)-N~2~-(methanesulfonyl)-N-(2-methoxy-5-methylphenyl)glycinamide
CAS No.:4370-87-0
Molecular Formula:C18H21ClN2O5S
Molecular Weight:412.8877
Hs Code.:2912299000
DSSTox Substance ID:DTXSID80361787
Wikidata:Q82144304

Synonyms:4370-87-0;CBKinase1_001848;CBKinase1_014248;DTXSID80361787;STK917528;AKOS005640410;SR-01000234666;SR-01000234666-1;BRD-K28021482-001-01-4;N~2~-(5-chloro-2-methoxyphenyl)-N-(2-methoxy-5-methylphenyl)-N~2~-(methylsulfonyl)glycinamide;N~2~-(5-Chloro-2-methoxyphenyl)-N~2~-(methanesulfonyl)-N-(2-methoxy-5-methylphenyl)glycinamide

Suppliers and Price of N~2~-(5-Chloro-2-methoxyphenyl)-N~2~-(methanesulfonyl)-N-(2-methoxy-5-methylphenyl)glycinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of N~2~-(5-Chloro-2-methoxyphenyl)-N~2~-(methanesulfonyl)-N-(2-methoxy-5-methylphenyl)glycinamide

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：96.81000
Density:1.366g/cm³
LogP:4.80060
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:412.0859706
Heavy Atom Count:27
Complexity:597

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)OC)NC(=O)CN(C2=C(C=CC(=C2)Cl)OC)S(=O)(=O)C

Technology Process of N~2~-(5-Chloro-2-methoxyphenyl)-N~2~-(methanesulfonyl)-N-(2-methoxy-5-methylphenyl)glycinamide

There total 9 articles about N~2~-(5-Chloro-2-methoxyphenyl)-N~2~-(methanesulfonyl)-N-(2-methoxy-5-methylphenyl)glycinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 27064-03-5
S-phenyl methanethioate

: C₁₀H₁₁BrZn*LiCl

: 4370-87-0
2-methyl-2-phenyl-but-3-enal

Guidance literature:: In tetrahydrofuran; at -78 ℃; for 0.5h; Temperature; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.orglett.8b00360

Reference yield: 64.0%

: 100-52-7
benzaldehyde

: 500771-20-0
4-bromo-2-iodobut-2-ene

: 4370-87-0
2-methyl-2-phenyl-but-3-enal

: 75851-76-2,75851-77-3,124004-57-5,141423-28-1,52922-20-0
1-phenylpent-3-en-1-ol

: 1,3-diphenyl-2-methyl-2-vinylpropan-1,3-diol

: 1,5-diphenyl-2-methylpent-2-en-1,5-diol

Guidance literature:: benzaldehyde; 4-bromo-2-iodobut-2-ene; With indium; In tetrahydrofuran; at 20 ℃; for 3h;

With hydrogenchloride; In tetrahydrofuran; Further stages.;
DOI:10.1021/jo026609v