[(2E,4Z)-8-(tert-Butyl-dimethyl-silanyloxy)-4-triisopropylsilanyloxy-octa-2,4-dienyloxymethyl]-benzene

Base Information

• Chemical Name: [(2E,4Z)-8-(tert-Butyl-dimethyl-silanyloxy)-4-triisopropylsilanyloxy-octa-2,4-dienyloxymethyl]-benzene
• CAS No.: 924887-37-6
• Molecular Formula: C₃₀H₅₄O₃Si₂
• Molecular Weight: 518.928
• Mol file: 924887-37-6.mol

Synonyms:[(2E,4Z)-8-(tert-Butyl-dimethyl-silanyloxy)-4-triisopropylsilanyloxy-octa-2,4-dienyloxymethyl]-benzene

Chemical Property of [(2E,4Z)-8-(tert-Butyl-dimethyl-silanyloxy)-4-triisopropylsilanyloxy-octa-2,4-dienyloxymethyl]-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(2E,4Z)-8-(tert-Butyl-dimethyl-silanyloxy)-4-triisopropylsilanyloxy-octa-2,4-dienyloxymethyl]-benzene

There total 1 articles about [(2E,4Z)-8-(tert-Butyl-dimethyl-silanyloxy)-4-triisopropylsilanyloxy-octa-2,4-dienyloxymethyl]-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-benzyloxy-8-(tert-butyl-dimethyl-silanyloxy)-oct-2-en-4-one + triisopropylsilyl trifluoromethanesulfonate (80522-42-5) → [(2E,4Z)-8-(tert-Butyl-dimethyl-silanyloxy)-4-triisopropylsilanyloxy-octa-2,4-dienyloxymethyl]-benzene (924887-37-6)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃;

DOI:10.1002/anie.200501345

Reference yield: 84.0%

[(2E,4Z)-8-(tert-Butyl-dimethyl-silanyloxy)-4-triisopropylsilanyloxy-octa-2,4-dienyloxymethyl]-benzene (924887-37-6) + C8H6Cl3N3O2 → 6-benzyloxymethyl-3-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-2-pyridin-2-yl-4-triisopropylsilanyloxy-3,6-dihydro-2H-pyridazine-1-carboxylic acid 2,2,2-trichloro-ethyl ester

Guidance literature:

With silver trifluoromethanesulfonate; (R)-2,2'-bis(diphenylphosphanyl)-1,1'-binaphthyl; In various solvent(s); at -78 - -40 ℃; for 4h;

DOI:10.1021/ja066726y

Reference yield:

[(2E,4Z)-8-(tert-Butyl-dimethyl-silanyloxy)-4-triisopropylsilanyloxy-octa-2,4-dienyloxymethyl]-benzene (924887-37-6) + 2-methyl-6-nitrosopyridine (688035-62-3) → 6-benzyloxymethyl-3-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-2-(6-methyl-pyridin-2-yl)-4-triisopropylsilanyloxy-3,6-dihydro-2H-[1,2]oxazine + 6-benzyloxymethyl-3-[3-(tert-butyl-dimethyl-silanyloxy)-propyl]-2-(6-methyl-pyridin-2-yl)-4-triisopropylsilanyloxy-3,6-dihydro-2H-[1,2]oxazine

Guidance literature:

With (S)-2,2'-bis(PPh₂)-5,6:5',6'-bis(OCF₂O)-1,1'-biphenyl; tetrakis(actonitrile)copper(I) hexafluorophosphate; In dichloromethane; at -85 - -20 ℃; for 6h; Title compound not separated from byproducts;

DOI:10.1002/anie.200501345

upstream raw materials:

triisopropylsilyl trifluoromethanesulfonate