4-{4-[(3R,4R)-3-amino-4-(2,5-difluorophenyl)piperidin-1-yl]phenoxymethyl}piperidine-1-carboxylic acid isopropyl ester hydrochloride

Base Information

Chemical Name:4-{4-[(3R,4R)-3-amino-4-(2,5-difluorophenyl)piperidin-1-yl]phenoxymethyl}piperidine-1-carboxylic acid isopropyl ester hydrochloride
CAS No.:1351338-43-6
Molecular Formula:C₂₇H₃₅F₂N₃O₃*ClH
Molecular Weight:524.051
Hs Code.:

Synonyms:4-{4-[(3R,4R)-3-amino-4-(2,5-difluorophenyl)piperidin-1-yl]phenoxymethyl}piperidine-1-carboxylic acid isopropyl ester hydrochloride

Suppliers and Price of 4-{4-[(3R,4R)-3-amino-4-(2,5-difluorophenyl)piperidin-1-yl]phenoxymethyl}piperidine-1-carboxylic acid isopropyl ester hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-{4-[(3R,4R)-3-amino-4-(2,5-difluorophenyl)piperidin-1-yl]phenoxymethyl}piperidine-1-carboxylic acid isopropyl ester hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-{4-[(3R,4R)-3-amino-4-(2,5-difluorophenyl)piperidin-1-yl]phenoxymethyl}piperidine-1-carboxylic acid isopropyl ester hydrochloride

There total 1 articles about 4-{4-[(3R,4R)-3-amino-4-(2,5-difluorophenyl)piperidin-1-yl]phenoxymethyl}piperidine-1-carboxylic acid isopropyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1032824-90-0
1-methylethyl 4-{[(4-bromophenyl)oxy]methyl}-1-piperidinecarboxylate

: 1245078-67-4
[(3R,4R)-4-(2,5-difluorophenyl)piperidin-3-yl]carbamic acid tert-butyl ester

: 1351338-43-6
4-{4-[(3R,4R)-3-amino-4-(2,5-difluorophenyl)piperidin-1-yl]phenoxymethyl}piperidine-1-carboxylic acid isopropyl ester hydrochloride

Guidance literature:: 1-methylethyl 4-{[(4-bromophenyl)oxy]methyl}-1-piperidinecarboxylate; [(3R,4R)-4-(2,5-difluorophenyl)piperidin-3-yl]carbamic acid tert-butyl ester; With triethylamine; In dichloromethane; at 20 ℃; for 80h; Molecular sieve;

With ammonium hydroxide; In methanol;

With hydrogenchloride; In 1,4-dioxane;