1-[[4-[4-(1-Pyrrolidinyl)-1-butyn-1-yl]phenyl]methyl]piperidine

Base Information Edit

Chemical Name:1-[[4-[4-(1-Pyrrolidinyl)-1-butyn-1-yl]phenyl]methyl]piperidine
CAS No.:544707-21-3
Molecular Formula:C₂₀H₂₈N₂
Molecular Weight:296.456
Hs Code.:
DSSTox Substance ID:DTXSID801175264
Pharos Ligand ID:HKN4JUF5FQ49
ChEMBL ID:CHEMBL574721
Mol file:544707-21-3.mol

Synonyms:CHEMBL574721;SCHEMBL3902545;DTXSID801175264;BDBM50414811;1-[[4-[4-(1-Pyrrolidinyl)-1-butyn-1-yl]phenyl]methyl]piperidine;544707-21-3

Suppliers and Price of 1-[[4-[4-(1-Pyrrolidinyl)-1-butyn-1-yl]phenyl]methyl]piperidine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-[[4-[4-(1-Pyrrolidinyl)-1-butyn-1-yl]phenyl]methyl]piperidine Edit

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:296.225248902
Heavy Atom Count:22
Complexity:371

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Canonical SMILES:C1CCN(CC1)CC2=CC=C(C=C2)C#CCCN3CCCC3

Technology Process of 1-[[4-[4-(1-Pyrrolidinyl)-1-butyn-1-yl]phenyl]methyl]piperidine

There total 2 articles about 1-[[4-[4-(1-Pyrrolidinyl)-1-butyn-1-yl]phenyl]methyl]piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

: 178162-69-1
1-(4-bromobenzyl)piperidine

: 14731-40-9
1-(but-3-ynyl)pyrrolidine

: 544707-21-3
1-[4-(4-(pyrrolidin-1-yl)but-1-ynyl)benzyl]piperidine

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine; triphenylphosphine; In N,N-dimethyl-formamide; at 20 - 125 ℃; for 1h; Inert atmosphere;
DOI:10.1016/j.ejmech.2009.04.049