Morpholine, 4-(N-phenylglycyl)-

Base Information

Chemical Name:Morpholine, 4-(N-phenylglycyl)-
CAS No.:91557-46-9
Molecular Formula:C12H16N2O2
Molecular Weight:220.2676
Hs Code.:
DSSTox Substance ID:DTXSID80238627
Nikkaji Number:J75.108A
Wikidata:Q83120916

Synonyms:4-(N-Phenylglycyl)morpholine;Morpholine, 4-(N-phenylglycyl)-;FC 32;BRN 0178519;91557-46-9;4-27-00-00490 (Beilstein Handbook Reference);DTXSID80238627;AKOS000253522;LS-93288;Z104583976

Suppliers and Price of Morpholine, 4-(N-phenylglycyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Morpholine, 4-(N-phenylglycyl)-

Chemical Property:

Vapor Pressure:4.73E-08mmHg at 25°C
Boiling Point:443.2°C at 760 mmHg
Flash Point:221.8°C
Density:1.199g/cm³
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:220.121177757
Heavy Atom Count:16
Complexity:221

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C(=O)CNC2=CC=CC=C2

Technology Process of Morpholine, 4-(N-phenylglycyl)-

There total 4 articles about Morpholine, 4-(N-phenylglycyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 110-91-8,99108-56-2
morpholine

: 103-01-5
N-Phenylglycine

: 91557-46-9
4-(N-phenyl-glycyl)-morpholine

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1021/acs.orglett.0c01574

Reference yield: 64.0%

: 1421132-82-2
C₆H₁₀NO₆S^(1-)*Na⁽¹⁺⁾

: 62-53-3
aniline

: 91557-46-9
4-(N-phenyl-glycyl)-morpholine

Guidance literature:: With 2-picoline borane complex; sodium acetate; In methanol; at 30 ℃; for 18h;
DOI:10.1021/jo3023878

Reference yield:

: 16423-59-9
2-(morpholin-4-yl)-2-oxoacetaldehyde

: 91557-46-9
4-(N-phenyl-glycyl)-morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: water; sodium metabisulfite / ethanol / Inert atmosphere

2: 2-picoline borane complex; sodium acetate / methanol / 18 h / 30 °C

With sodium metabisulfite; 2-picoline borane complex; water; sodium acetate; In methanol; ethanol;
DOI:10.1021/jo3023878