Morpholine, 4-(oxoacetyl)-

Base Information

Chemical Name:Morpholine, 4-(oxoacetyl)-
CAS No.:16423-59-9
Molecular Formula:C6H9NO3
Molecular Weight:143.142
Hs Code.:
DSSTox Substance ID:DTXSID50444930
Nikkaji Number:J1.286.029C
Wikidata:Q82263212
Mol file:16423-59-9.mol

Synonyms:Morpholine, 4-(oxoacetyl)-;2-Morpholinoglyoxal;16423-59-9;SCHEMBL1896875;DTXSID50444930

Suppliers and Price of Morpholine, 4-(oxoacetyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Morpholine, 4-(oxoacetyl)-

Chemical Property:

XLogP3:-0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:143.058243149
Heavy Atom Count:10
Complexity:140

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C(=O)C=O

Technology Process of Morpholine, 4-(oxoacetyl)-

There total 1 articles about Morpholine, 4-(oxoacetyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4394-85-8
4-morpholinecarboxaldehyde

: 4111-55-1
lithium dicyclohexylamide

: 110-91-8,99108-56-2
morpholine

: 16423-59-9
2-(morpholin-4-yl)-2-oxoacetaldehyde

: lithium; 1,2-di-morpholin-4-yl-2-oxo-ethanolate

: C₂O₂Li(NC₄H₈O)2^(1-)*Li⁽¹⁺⁾

Guidance literature:: In tetrahydrofuran; benzene-d6; at 20 ℃; for 0.25h; Product distribution;
DOI:10.1021/jo9908445

Reference yield:

: 16423-59-9
2-(morpholin-4-yl)-2-oxoacetaldehyde

: 1167458-15-2
(Z)-N,N-dimethyl-5-phenyl-2-propionylpent-2-enamide

: (2S,3S)-N,N-dimethyl-5-morpholino-4,5-dioxo-3-phenethyl-2-propionylpentanamide

: 1167458-32-3
(2R,3R)-N,N-dimethyl-5-morpholino-4,5-dioxo-3-phenethyl-2-propionylpentanamide

Guidance literature:: With BF₄^(1-)*C₁₈H₁₃F₅N₃⁽¹⁺⁾; magnesium sulfate; N-ethyl-N,N-diisopropylamine; In tetrachloromethane; at 0 ℃; for 12h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol901081a

Reference yield:

: 16423-59-9
2-(morpholin-4-yl)-2-oxoacetaldehyde

: 1167458-22-1
(Z)-2-(3-(4-chlorophenyl)propylidene)-N,N-dimethyl-3-oxohexanamide

: 2-(5-(4-chlorophenyl)-1-morpholino-1,2-dioxopentan-3-yl)-N,N-dimethyl-3-oxohexanamide

: 1167458-51-6
(R)-2-((R)-5-(4-chlorophenyl)-1-morpholino-1,2-dioxopentan-3-yl)-N,N-dimethyl-3-oxohexanamide

Guidance literature:: With BF₄^(1-)*C₁₈H₁₃F₅N₃⁽¹⁺⁾; magnesium sulfate; N-ethyl-N,N-diisopropylamine; In tetrachloromethane; at 0 ℃; for 12h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol901081a