GALANTHAMINE HYDROBROMIDE

Base Information

• Chemical Name: GALANTHAMINE HYDROBROMIDE
• CAS No.: 69353-21-5
• Molecular Formula: C17H21 N O3 . Br H
• Molecular Weight: 368.31
• Hs Code.: 2942000000
• Mol file: 69353-21-5.mol

Synonyms:Benzofuro[4,3,2-efg]-2-benzazocin-6-ol,1,2,3,4,6,7,7a,11c-octahydro-9-methoxy-2-methyl-, hydrobromide

Chemical Property of GALANTHAMINE HYDROBROMIDE

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 287oC decomposes
• Boiling Point: 630.4 °C at 760 mmHg
• Flash Point: 335 °C
• PSA: 18.46000
• Density: 1.593 g/cm³
• LogP: 3.58460
• Storage Temp.: −20°C

Purity/Quality:

99% ^*data from raw suppliers

Galanthamine, Hydrobromide A competitive and reversible inhibitor of acetylcholinesterase. ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Clinical Use: Galantamine, which was introduced in 2001, is an alkaloid found in plants of the family Amaryllidaceae, which includes the daffodil (Narcissus pseudonarcissus) and snowflake (Leucojum aestivum). It is a reversible inhibitor of AChE, but it does not appear to inhibit butyrylcholinesterase. Because it is a tertiary amine and can cross the blood-brain barrier, it is indicated for treatment of mild-to-moderate AD and dementia. It has been used outside the U.S. for more than 30 years as an anticurare agent in anesthesia. Galantamine differs from other cholinesterase inhibitors, because it allosterically binds to nicotinic receptors, giving it a dual cholinergic action.