Bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethyl}-carbamic acid benzyl ester

Base Information

• Chemical Name: Bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethyl}-carbamic acid benzyl ester
• CAS No.: 204527-45-7
• Molecular Formula: C₂₀H₃₃NO₈
• Molecular Weight: 415.484
• Mol file: 204527-45-7.mol

Synonyms:Bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethyl}-carbamic acid benzyl ester

Chemical Property of Bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethyl}-carbamic acid benzyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of Bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethyl}-carbamic acid benzyl ester

There total 1 articles about Bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethyl}-carbamic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3,6,12,15-tetraoxa-9-azaheptadecane-1,17-diol (25743-12-8) + benzyl chloroformate (501-53-1,94274-21-2) → Bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethyl}-carbamic acid benzyl ester (204527-45-7)

Guidance literature:

With potassium carbonate; In ethanol; for 12h; Ambient temperature;

DOI:10.3891/acta.chem.scand.52-0374

Reference yield: 80.0%

p-toluenesulfonyl chloride (98-59-9) + Bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethyl}-carbamic acid benzyl ester (204527-45-7) → C34H45NO12S2 (204527-46-8)

Guidance literature:

With pyridine; dmap; In dichloromethane; for 12h; Ambient temperature;

DOI:10.3891/acta.chem.scand.52-0374

Reference yield:

Bis-{2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethyl}-carbamic acid benzyl ester (204527-45-7) → C44H45N3O8

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / DMAP, pyridine / CH₂Cl₂ / 12 h / Ambient temperature

2: 98 percent / NaI / acetone / 12 h / Heating

3: 40 percent / Cs₂CO₃ / dimethylformamide / 24 h / 60 °C

With pyridine; dmap; caesium carbonate; sodium iodide; In dichloromethane; N,N-dimethyl-formamide; acetone;

DOI:10.3891/acta.chem.scand.52-0374

upstream raw materials:

3,6,12,15-tetraoxa-9-azaheptadecane-1,17-diol

benzyl chloroformate

Downstream raw materials:

C₃₄H₄₅NO₁₂S₂

Bis-{2-[2-(2-iodo-ethoxy)-ethoxy]-ethyl}-carbamic acid benzyl ester