N⁴-benzoyl-2'-O-phenoxythiocarbonyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5'-13C]cytidine

Base Information

• Chemical Name: N⁴-benzoyl-2'-O-phenoxythiocarbonyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5'-13C]cytidine
• CAS No.: 445433-98-7
• Molecular Formula: C₃₅H₄₇N₃O₈SSi₂
• Molecular Weight: 726.999

Synonyms:N⁴-benzoyl-2'-O-phenoxythiocarbonyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5'-13C]cytidine

Chemical Property of N⁴-benzoyl-2'-O-phenoxythiocarbonyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5'-13C]cytidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N⁴-benzoyl-2'-O-phenoxythiocarbonyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5'-13C]cytidine

There total 6 articles about N⁴-benzoyl-2'-O-phenoxythiocarbonyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5'-13C]cytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

phenylcarbonochloridothioate (1005-56-7) + N4-benzoyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5-13C]cytidine (445433-94-3) → N4-benzoyl-2'-O-phenoxythiocarbonyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5'-13C]cytidine (445433-98-7)

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1021/jo016281q

Reference yield:

1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-[5-13C]ribose (54447-56-2) → N4-benzoyl-2'-O-phenoxythiocarbonyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5'-13C]cytidine (445433-98-7)

Guidance literature:

Multi-step reaction with 4 steps

1: 96 percent / trimethylsilyl trifluoromethanesulfonate / toluene / 80 °C

2: NaOH; pyridine / methanol; H₂O

3: 231 mg / pyridine

4: 86 percent / pyridine / 20 °C

With pyridine; sodium hydroxide; trimethylsilyl trifluoromethanesulfonate; In methanol; water; toluene;

DOI:10.1021/jo016281q

Reference yield:

methyl 2,3,5-tri-O-benzoyl-D-[5-13C]ribofuranoside (184000-83-7) → N4-benzoyl-2'-O-phenoxythiocarbonyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5'-13C]cytidine (445433-98-7)

Guidance literature:

Multi-step reaction with 5 steps

1: H₂SO₄; AcOH / 3 h / 0 °C

2: 96 percent / trimethylsilyl trifluoromethanesulfonate / toluene / 80 °C

3: NaOH; pyridine / methanol; H₂O

4: 231 mg / pyridine

5: 86 percent / pyridine / 20 °C

With pyridine; sodium hydroxide; trimethylsilyl trifluoromethanesulfonate; sulfuric acid; acetic acid; In methanol; water; toluene;

DOI:10.1021/jo016281q

upstream raw materials:

phenylcarbonochloridothioate

N⁴-benzoyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5-13C]cytidine

1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-[5-13C]ribose

1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane

Downstream raw materials:

N⁴-benzoyl-2'-deoxy-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5'-13C]cytidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 445433-98-7 N⁴-benzoyl-2'-O-phenoxythiocarbonyl-3',5'-O-1,1,3,3-tetraisopropyldisiloxane-1,3-diyl[5'-13C]cytidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send