(1-tert-butylsulfanyl)-3-chloro-2-(2,2-dibromovinyl)benzene

Base Information

• Chemical Name: (1-tert-butylsulfanyl)-3-chloro-2-(2,2-dibromovinyl)benzene
• CAS No.: 1191415-71-0
• Molecular Formula: C₁₂H₁₃Br₂ClS
• Molecular Weight: 384.562
• Mol file: 1191415-71-0.mol

Synonyms:(1-tert-butylsulfanyl)-3-chloro-2-(2,2-dibromovinyl)benzene

Chemical Property of (1-tert-butylsulfanyl)-3-chloro-2-(2,2-dibromovinyl)benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1-tert-butylsulfanyl)-3-chloro-2-(2,2-dibromovinyl)benzene

There total 2 articles about (1-tert-butylsulfanyl)-3-chloro-2-(2,2-dibromovinyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

carbon tetrabromide (558-13-4) + 2-(tert-butylsulfanyl)-6-chlorobenzaldehyde (1191415-70-9) → (1-tert-butylsulfanyl)-3-chloro-2-(2,2-dibromovinyl)benzene (1191415-71-0)

Guidance literature:

With triphenylphosphine; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1002/anie.200902843 DOI:10.1039/b912093a

Reference yield:

2-chloro-6-fluorobenzaldehyde (387-45-1) → (1-tert-butylsulfanyl)-3-chloro-2-(2,2-dibromovinyl)benzene (1191415-71-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: triphenylphosphine / dichloromethane / 2 h / 0 - 20 °C / Inert atmosphere

With sodium hydride; triphenylphosphine; In dichloromethane; N,N-dimethyl-formamide; mineral oil;

DOI:10.1002/ejoc.201600333

Reference yield: 70.0%

(1-tert-butylsulfanyl)-3-chloro-2-(2,2-dibromovinyl)benzene (1191415-71-0) → 3-chloro-2-(2,2-dibromovinyl)benzenethiol (1191415-32-3)

Guidance literature:

With toluene-4-sulfonic acid; In water; toluene; at 110 ℃; Dean-Stark; Inert atmosphere;

DOI:10.1002/ejoc.201600333

upstream raw materials:

carbon tetrabromide

2-(tert-butylsulfanyl)-6-chlorobenzaldehyde

2-chloro-6-fluorobenzaldehyde

Downstream raw materials:

3-chloro-2-(2,2-dibromovinyl)benzenethiol