(S)-((R)-oxiran-2-yl)(phenyl)methanol

Base Information

• Chemical Name: (S)-((R)-oxiran-2-yl)(phenyl)methanol
• CAS No.: 91420-78-9
• Molecular Formula: C₉H₁₀O₂
• Molecular Weight: 150.177
• Mol file: 91420-78-9.mol

Synonyms:(S)-((R)-oxiran-2-yl)(phenyl)methanol

Chemical Property of (S)-((R)-oxiran-2-yl)(phenyl)methanol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (S)-((R)-oxiran-2-yl)(phenyl)methanol

There total 20 articles about (S)-((R)-oxiran-2-yl)(phenyl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(1S,2R)-benzoic acid oxiranyl-phenyl-methyl ester → (S)-((R)-oxiran-2-yl)(phenyl)methanol (91420-78-9)

Guidance literature:

With methanol; sodium hydride; In tetrahydrofuran; at 20 ℃; for 18h;

DOI:10.1039/b404389h

Reference yield: 48.0%

1-Phenyl-2-propen-1-ol (4393-06-0) → (S)-((R)-oxiran-2-yl)(phenyl)methanol (91420-78-9)

Guidance literature:

1-Phenyl-2-propen-1-ol; With titanium(IV) isopropylate; L-(+)-diisopropyl tartrate; In dichloromethane; at -20 ℃; Molecular sieve; Sealed tube;

With tert.-butylhydroperoxide; In decane; dichloromethane; at -20 ℃; for 15h; enantioselective reaction; Molecular sieve; Sealed tube;

DOI:10.1039/c5ob01808k

Reference yield: 47.0%

1-Phenyl-2-propen-1-ol (4393-06-0) → (1S)-1-phenylprop-2-en-1-ol (104713-12-4) + (S)-((R)-oxiran-2-yl)(phenyl)methanol (91420-78-9)

Guidance literature:

With C₉₆H₁₄₂N₂O₄; WO₂(acac)₂; dihydrogen peroxide; sodium chloride; In dichloromethane; water; at 20 ℃; for 24h; enantioselective reaction; Green chemistry;

DOI:10.1021/ja411379e

upstream raw materials:

vinyl acetate

2(R*),3-epoxy-1(S*)-phenylpropan-1-ol

1-Phenyl-2-propen-1-ol

(+)-(1S,2S)-2-(dimethylamino)-1-phenylpropane-1,3-diol

Downstream raw materials:

(1R,2R)-2,3-epoxy-1-phenylpropan-1-ol

(S)-2-[(R)-(5-Methoxy-2-vinyl-phenoxy)-phenyl-methyl]-oxirane

(S)-2-[(R)-Phenyl-(2-vinyl-phenoxy)-methyl]-oxirane

1-((S)-1-Phenyl-allyloxy)-2-vinyl-benzene