(R)-1-Phenyl-2-propen-1-ol

Base Information

• Chemical Name: (R)-1-Phenyl-2-propen-1-ol
• CAS No.: 104713-12-4
• Molecular Formula: C9H10 O
• Molecular Weight: 134.178
• Hs Code.: 2906299090
• European Community (EC) Number: 635-169-5
• Nikkaji Number: J415.683H
• Mol file: 104713-12-4.mol

Synonyms:(R)-1-Phenyl-2-propen-1-ol;104713-12-4;(1R)-1-phenylprop-2-en-1-ol;(R)-1-Phenylallyl alcohol;(R)-alpha-Vinylbenzyl alcohol;(+)(R)-Phenyl-vinyl-carbinol;SCHEMBL13090620;(R)-1-phenylprop-2-en-1-ol;MHHJQVRGRPHIMR-SECBINFHSA-N;AKOS025294013;EN300-7344512;J-001235;(R)-1-Phenyl-2-propen-1-ol, technical, >=95% (sum of enantiomers, GC)

Chemical Property of (R)-1-Phenyl-2-propen-1-ol

Chemical Property:

• Refractive Index: n20/D 1.543
• PSA: 20.23000
• Density: 1.021 g/mL at 20 °C(lit.)
• LogP: 1.90600
• Storage Temp.: −20°C
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 134.073164938
• Heavy Atom Count: 10
• Complexity: 103

Purity/Quality:

98%,99%, ^*data from raw suppliers

(R)-1-PHENYL-2-PROPEN-1-OL 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C=CC(C1=CC=CC=C1)O
• Isomeric SMILES: C=C[C@H](C1=CC=CC=C1)O

Technology Process of (R)-1-Phenyl-2-propen-1-ol

There total 323 articles about (R)-1-Phenyl-2-propen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

vinyl acetate (108-05-4,9003-20-7) + 1-Phenyl-2-propen-1-ol (4393-06-0) → (1S)-1-phenylprop-2-en-1-ol (104713-12-4) + (R)-(+)-1-acetoxy-1-phenyl-2-propylene (7217-71-2,82999-01-7,129646-79-3)

Guidance literature:

With novozyme 435; In toluene; at 20 ℃; for 12h;

DOI:10.1021/ol702115h

Reference yield: 47.0%

Isopropenyl acetate (108-22-5) + 1-Phenyl-2-propen-1-ol (4393-06-0) → (1S)-1-phenylprop-2-en-1-ol (104713-12-4) + (R)-(+)-1-acetoxy-1-phenyl-2-propylene (7217-71-2,82999-01-7,129646-79-3)

Guidance literature:

With Novozyme 435; In toluene; at 40 ℃; for 16h; Molecular sieve; Enzymatic reaction;

DOI:10.1021/jo801874r

Reference yield: 38.0%

Isopropenyl acetate (108-22-5) + 1-Phenyl-2-propen-1-ol (4393-06-0) → 1-phenyl-2-propenyl acetate (7217-71-2) + (R)-1-phenylprop-2-en-1-ol (104713-12-4) + (1S)-1-phenylprop-2-en-1-ol (104713-12-4) + 1-phenyl-propan-1-one (93-55-0)

Guidance literature:

With Novozym 435; potassium tert-butylate; sodium carbonate; [2,3,4,5-Ph4(η⁵-C4CNH(i-Pr))]Ru(CO)2Cl; In toluene; at 25 ℃; for 96h;

DOI:10.1021/jo0355799

upstream raw materials:

phthalic acid mono-((R)-1-phenyl-allyl ester)

1-Phenyl-2-propen-1-ol

1-phenyl-3-phenylseleno-1-propene

(1R,3S,4S)-3-Bromo-7-[(2R,3R)-3-(2-chloro-5-nitro-phenyl)-oxaziridine-2-sulfonylmethyl]-1,7-dimethyl-bicyclo[2.2.1]heptan-2-one

Downstream raw materials:

(R)-1-phenyl-1-propanol

((R)-1-Phenyl-ethyl)-carbamic acid (R)-1-phenyl-allyl ester

(1'R)-phenyl 2'-propenyl 2-butynoate

Diphenyl-bis-((R)-1-phenyl-allyloxy)-silane