[2-[2-(Benzoyloxy)-5-bromophenyl]-1H-imidazol-1-yl]phenylmethanone

Base Information

Chemical Name:[2-[2-(Benzoyloxy)-5-bromophenyl]-1H-imidazol-1-yl]phenylmethanone
CAS No.:289506-18-9
Molecular Formula:C₂₃H₁₅BrN₂O₃
Molecular Weight:447.288
Hs Code.:
DSSTox Substance ID:DTXSID901166383

Synonyms:DTXSID901166383;[2-[2-(Benzoyloxy)-5-bromophenyl]-1H-imidazol-1-yl]phenylmethanone;289506-18-9

Suppliers and Price of [2-[2-(Benzoyloxy)-5-bromophenyl]-1H-imidazol-1-yl]phenylmethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [2-[2-(Benzoyloxy)-5-bromophenyl]-1H-imidazol-1-yl]phenylmethanone

Chemical Property:

XLogP3:5.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:446.02660
Heavy Atom Count:29
Complexity:575

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)N2C=CN=C2C3=C(C=CC(=C3)Br)OC(=O)C4=CC=CC=C4

Technology Process of [2-[2-(Benzoyloxy)-5-bromophenyl]-1H-imidazol-1-yl]phenylmethanone

There total 2 articles about [2-[2-(Benzoyloxy)-5-bromophenyl]-1H-imidazol-1-yl]phenylmethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 98-88-4
benzoyl chloride

: 289506-17-8
2’-(2-hydroxy-5-bromophenyl)imidazole

: 289506-18-9
2-(1-benzoyl-1H-imidazol-2-yl)-4-bromophenyl benzoate

Guidance literature:: With triethylamine; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/jo000014n

Reference yield:

: 22532-62-3
4-bromosalicylaldehyde

: 289506-18-9
2-(1-benzoyl-1H-imidazol-2-yl)-4-bromophenyl benzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / Inert atmosphere; Reflux

1.2: 4 h / Reflux; Inert atmosphere

2.1: triethylamine / tetrahydrofuran

With acetic acid; triethylamine; In tetrahydrofuran;
DOI:10.1039/c8nj02818d

Reference yield: 85.0%

: 7486-35-3
tri-n-butyl(vinyl)tin

: 289506-18-9
2-(1-benzoyl-1H-imidazol-2-yl)-4-bromophenyl benzoate

: 289506-19-0
2-(1-benzoyl-1H-imidazol-2-yl)-4-vinylphenyl benzoate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; 3,5-Di-tert-butylcatechol; In toluene; for 5h; Inert atmosphere; Reflux;
DOI:10.1039/c8nj02818d