2-BUTYLCYCLOHEXANOL

Base Information

• Chemical Name: 2-BUTYLCYCLOHEXANOL
• CAS No.: 36159-49-6
• Molecular Formula: C10H20O
• Molecular Weight: 156.268
• Hs Code.: 2906199090
• Mol file: 36159-49-6.mol

Synonyms:Cyclohexanol,2-butyl;1-n-Butylcyclohexanol;2-N-BUTYL-1-CYCLOHEXANOL;2-Butylcyclohexane-1-ol;2-Butyl-cyclohexanol;2-n-butylcyclohexanol;

Chemical Property of 2-BUTYLCYCLOHEXANOL

Chemical Property:

• Vapor Pressure: 0.0276mmHg at 25°C
• Melting Point: 66.81°C (estimate)
• Refractive Index: 1.4583 (estimate)
• Boiling Point: 217.9°C at 760 mmHg
• PKA: 15.33±0.40(Predicted)
• Flash Point: 87.9°C
• PSA: 20.23000
• Density: 0.897g/cm³
• LogP: 2.72770

Purity/Quality:

99% ^*data from raw suppliers

2-N-Butyl-1-cyclohexanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 2-BUTYLCYCLOHEXANOL

There total 7 articles about 2-BUTYLCYCLOHEXANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

1-allyloxy-2-butyl-cyclohexane → 2-n-butylcyclohexanol (36159-49-6)

Guidance literature:

1-allyloxy-2-butyl-cyclohexane; Grubbs catalyst first generation; In dichloromethane; at 20 ℃; for 12h;

With hydrogenchloride;

DOI:10.1016/S0040-4039(02)00141-7

Reference yield: 63.0%

cyclohexane-1,2-epoxide (286-20-4) + lithium di-tert-butylphosphido(n-butyl)cuprate → 2-n-butylcyclohexanol (36159-49-6)

Guidance literature:

In tetrahydrofuran; react. of Cu complex with organic electrophile at 0°C, 4 h;

DOI:10.1021/ja00229a054

Reference yield: 39.0%

vinyl acetate (108-05-4,9003-20-7) + cis-2-butylcyclohexanol (35242-02-5) → cis-2-Butyl-cyclohexanol (612040-80-9) + cis-2-Butylcyclohexanol (35242-02-5,35242-05-8,36159-49-6) + Acetic acid (1R,2S)-2-butyl-cyclohexyl ester

Guidance literature:

With 4 A molecular sieve; Lipase PS (Amano); In toluene; at 30 ℃; for 51h;

DOI:10.1016/S0040-4039(03)01514-4

upstream raw materials:

n-butyllithium

diethyl ether

cyclohexane-1,2-epoxide

vinyl acetate

Downstream raw materials:

2-butylcyclohexanone

Refernces

• 1、 Cadot, Christine,Dalko, Peter I,Cossy, Janine. "Olefin isomerization by a ruthenium carbenoid complex. Cleavage of allyl and homoallyl groups". . p. 1839 - 1841. Retrieved 2007/10/03.