1-(4-((2R,3R)-3-(benzyloxy)-2-hydroxy-3-phenylpropoxy)phenyl)ethanone

Base Information

• Chemical Name: 1-(4-((2R,3R)-3-(benzyloxy)-2-hydroxy-3-phenylpropoxy)phenyl)ethanone
• CAS No.: 1445828-44-3
• Molecular Formula: C₂₄H₂₄O₄
• Molecular Weight: 376.452
• Mol file: 1445828-44-3.mol

Synonyms:1-(4-((2R,3R)-3-(benzyloxy)-2-hydroxy-3-phenylpropoxy)phenyl)ethanone

Chemical Property of 1-(4-((2R,3R)-3-(benzyloxy)-2-hydroxy-3-phenylpropoxy)phenyl)ethanone

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 1-(4-((2R,3R)-3-(benzyloxy)-2-hydroxy-3-phenylpropoxy)phenyl)ethanone

There total 2 articles about 1-(4-((2R,3R)-3-(benzyloxy)-2-hydroxy-3-phenylpropoxy)phenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

(±)-2-((benzyloxy)(phenyl)methyl)oxirane + 4-Hydroxyacetophenone (99-93-4) → (S)-2-((S)-(benzyloxy)(phenyl)methyl)oxirane (1239892-67-1) + 1-(4-((2R,3R)-3-(benzyloxy)-2-hydroxy-3-phenylpropoxy)phenyl)ethanone (1445828-44-3)

Guidance literature:

(±)-2-((benzyloxy)(phenyl)methyl)oxirane; 4-Hydroxyacetophenone; With (R,R)-Cobalt Jacobsen catalyst; In tert-butyl methyl ether; at 25 - 35 ℃; Molecular sieve;

With pyridinium p-toluenesulfonate; In tert-butyl methyl ether;

Reference yield: 89.0%

(±)-2-((benzyloxy)(phenyl)methyl)oxirane + 4-Hydroxyacetophenone (99-93-4) → 1-(4-((2R,3R)-3-(benzyloxy)-2-hydroxy-3-phenylpropoxy)phenyl)ethanone (1445828-44-3)

Guidance literature:

With C₄₀H₅₂CoF₉N₂O₃*H₂O; In tert-butyl methyl ether; at 25 ℃; Molecular sieve;

DOI:10.1039/c3ob42501k

upstream raw materials:

4-Hydroxyacetophenone