1,5-dihydro-3H-pyrrolo[4,3,2-de]isoquinoline-4-carboxylic acid benzyl ester

Base Information

• Chemical Name: 1,5-dihydro-3H-pyrrolo[4,3,2-de]isoquinoline-4-carboxylic acid benzyl ester
• CAS No.: 53462-91-2
• Molecular Formula: C₁₈H₁₆N₂O₂
• Molecular Weight: 292.337
• Mol file: 53462-91-2.mol

Synonyms:1,5-dihydro-3H-pyrrolo[4,3,2-de]isoquinoline-4-carboxylic acid benzyl ester

Chemical Property of 1,5-dihydro-3H-pyrrolo[4,3,2-de]isoquinoline-4-carboxylic acid benzyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 1,5-dihydro-3H-pyrrolo[4,3,2-de]isoquinoline-4-carboxylic acid benzyl ester

There total 2 articles about 1,5-dihydro-3H-pyrrolo[4,3,2-de]isoquinoline-4-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyrographite (7440-44-0) + benzyl chloroformate (501-53-1,94274-21-2) + 1,3,4,5-tetrahydro-pyrrolo[4,3,2-de]isoquinoline (53269-34-4) → 1,5-dihydro-3H-pyrrolo[4,3,2-de]isoquinoline-4-carboxylic acid benzyl ester (53462-91-2)

Guidance literature:

With triethylamine; In tetrahydrofuran; chloroform;

Reference yield:

→ 1,5-dihydro-3H-pyrrolo[4,3,2-de]isoquinoline-4-carboxylic acid benzyl ester (53462-91-2)

Guidance literature:

Isochinolin(17), Carbobenzoxychlorid;

DOI:10.1021/jm00257a003

upstream raw materials:

pyrographite

benzyl chloroformate

1,3,4,5-tetrahydro-pyrrolo[4,3,2-de]isoquinoline