1-diphenylphosphino-1'-(N-[carboxymethyl]carbamoyl)ferrocene

Base Information

• Chemical Name: 1-diphenylphosphino-1'-(N-[carboxymethyl]carbamoyl)ferrocene
• CAS No.: 1160484-19-4
• Molecular Formula: C₂₅H₂₂FeNO₃P
• Molecular Weight: 471.275
• Mol file: 1160484-19-4.mol

Synonyms:1-diphenylphosphino-1'-(N-[carboxymethyl]carbamoyl)ferrocene

Chemical Property of 1-diphenylphosphino-1'-(N-[carboxymethyl]carbamoyl)ferrocene

Chemical Property:

Purity/Quality:

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Technology Process of 1-diphenylphosphino-1'-(N-[carboxymethyl]carbamoyl)ferrocene

There total 1 articles about 1-diphenylphosphino-1'-(N-[carboxymethyl]carbamoyl)ferrocene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-diphenylphosphino-1'-(N-[(methoxycarbonyl)methyl]carbamoyl)ferrocene (1160484-10-5) + water (7732-18-5) → 1-diphenylphosphino-1'-(N-[carboxymethyl]carbamoyl)ferrocene (1160484-19-4)

Guidance literature:

With NaOH; In 1,4-dioxane; sodium hydroxide; aq. NaOH; (Ar, dark); addn. of aq. NaOH to dioxane soln. of ferrocene deriv., heatin at 50°C for overnight; cooling to 0°C, addn. of H3PO4 to pH 2, extn. (CH2Cl2), drying with MgSO4, evapn., chromy. (silica gel, CH2Cl2/methanol (1:1)), evapn., drying over NaOH, elem. anal.;

DOI:10.1021/om900209j

Reference yield:

sodium tetrachloropalladate(II) + 1-diphenylphosphino-1'-(N-[carboxymethyl]carbamoyl)ferrocene (1160484-19-4) + water (7732-18-5) → trans-[PdCl2(1-diphenylphosphino-1'-(N-[carboxymethyl]carbamoyl)ferrocene-κP)2]*3water

Guidance literature:

In acetic acid; aq. acetic acid; (Ar, dark); addn. of hot soln. of ferrocene deriv. in acetic acid to aq.soln. of palladium compd., keeping for several mins; drying vac., washing with aq. acetic acid, elem. anal.;

DOI:10.1021/om900209j

Reference yield:

[ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2 (52462-29-0) + 1-diphenylphosphino-1'-(N-[carboxymethyl]carbamoyl)ferrocene (1160484-19-4) → (Ph2PRuCl2(η6-p-cymene))(ferrocene-1,1'-diyl)C(O)NHCH2COOH (1373760-57-6)

Guidance literature:

In chloroform; (N2); exclusion of direct daylight; addn. of soln. of Ph2P(ferrocene-1,1'-diyl)C(O)NHCH2COOH (1 equiv.) in CHCl3 to ((η6-p-cymene)RuCl2)2 (0.5 equiv.), stirring at room temp. for 3 h; not isolated; monitoring by NMR;

DOI:10.1021/om3002087

upstream raw materials:

1-diphenylphosphino-1'-(N-[(methoxycarbonyl)methyl]carbamoyl)ferrocene

water

Downstream raw materials:

(Ph2PRuCl2(η6-p-cymene))(ferrocene-1,1'-diyl)C(O)NHCH2COOH