2H-1,4-Benzoxazine-4-hexanoic acid, 3,4-dihydro-2-[2-[2-(2-methoxy-2-oxoethyl)phenoxy]ethyl]-3-oxo-

Base Information

Chemical Name:2H-1,4-Benzoxazine-4-hexanoic acid, 3,4-dihydro-2-[2-[2-(2-methoxy-2-oxoethyl)phenoxy]ethyl]-3-oxo-
CAS No.:374109-32-7
Molecular Formula:C₂₅H₂₉NO₇
Molecular Weight:455.508
Hs Code.:

Synonyms:2H-1,4-Benzoxazine-4-hexanoic acid, 3,4-dihydro-2-[2-[2-(2-methoxy-2-oxoethyl)phenoxy]ethyl]-3-oxo-

Suppliers and Price of 2H-1,4-Benzoxazine-4-hexanoic acid, 3,4-dihydro-2-[2-[2-(2-methoxy-2-oxoethyl)phenoxy]ethyl]-3-oxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2H-1,4-Benzoxazine-4-hexanoic acid, 3,4-dihydro-2-[2-[2-(2-methoxy-2-oxoethyl)phenoxy]ethyl]-3-oxo-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2H-1,4-Benzoxazine-4-hexanoic acid, 3,4-dihydro-2-[2-[2-(2-methoxy-2-oxoethyl)phenoxy]ethyl]-3-oxo-

There total 7 articles about 2H-1,4-Benzoxazine-4-hexanoic acid, 3,4-dihydro-2-[2-[2-(2-methoxy-2-oxoethyl)phenoxy]ethyl]-3-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 374109-31-6
6-{2-[2-(2-methoxycarbonylmethyl-phenoxy)-ethyl]-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl}-hexanoic acid benzyl ester

: 374109-32-7
2H-1,4-Benzoxazine-4-hexanoic acid, 3,4-dihydro-2-[2-[2-(2-methoxy-2-oxoethyl)phenoxy]ethyl]-3-oxo-

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 20 ℃; for 3h; under 2585.74 Torr;
DOI:10.1021/jm0301888

Reference yield:

: 88-75-5,78813-12-4
2-hydroxynitrobenzene

: 374109-32-7
2H-1,4-Benzoxazine-4-hexanoic acid, 3,4-dihydro-2-[2-[2-(2-methoxy-2-oxoethyl)phenoxy]ethyl]-3-oxo-

Guidance literature:: Multi-step reaction with 6 steps

1.1: 62 percent / potassium carbonate / dimethylformamide / 17 h / 20 °C

2.1: H₂ / Pd/C / ethanol / 3 h / 20 °C / 2327.17 Torr

3.1: 46.8 g / imidazole / dimethylformamide / 15 h / 0 - 20 °C

4.1: sodium hydride / dimethylformamide / 0 °C

4.2: dimethylformamide / 0 - 20 °C

4.3: aq. CH₃SO₃H / methanol / 20 °C

5.1: tributylphosphine; 1,1'-(azodicarbonyl)dipiperidine / benzene / 20 °C

6.1: H₂ / Pd/C / ethanol / 3 h / 20 °C / 2585.74 Torr

With 1H-imidazole; tributylphosphine; hydrogen; sodium hydride; potassium carbonate; 1,1'-azodicarbonyl-dipiperidine; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide; benzene; 5.1: Mitsunobu reaction;
DOI:10.1021/jm0301888

Reference yield:

: 161176-99-4
3,4-Dihydro-2-(2-hydroxyethyl)-3-oxo-2H-1,4-benzoxazine

: 374109-32-7
2H-1,4-Benzoxazine-4-hexanoic acid, 3,4-dihydro-2-[2-[2-(2-methoxy-2-oxoethyl)phenoxy]ethyl]-3-oxo-

Guidance literature:: Multi-step reaction with 4 steps

1.1: 46.8 g / imidazole / dimethylformamide / 15 h / 0 - 20 °C

2.1: sodium hydride / dimethylformamide / 0 °C

2.2: dimethylformamide / 0 - 20 °C

2.3: aq. CH₃SO₃H / methanol / 20 °C

3.1: tributylphosphine; 1,1'-(azodicarbonyl)dipiperidine / benzene / 20 °C

4.1: H₂ / Pd/C / ethanol / 3 h / 20 °C / 2585.74 Torr

With 1H-imidazole; tributylphosphine; hydrogen; sodium hydride; 1,1'-azodicarbonyl-dipiperidine; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide; benzene; 3.1: Mitsunobu reaction;
DOI:10.1021/jm0301888