N--L-β-phenylalanine ethyl ester

Base Information

• Chemical Name: N--L-β-phenylalanine ethyl ester
• CAS No.: 118140-35-5
• Molecular Formula: C₂₂H₂₄N₂O₄
• Molecular Weight: 380.444
• Mol file: 118140-35-5.mol

Synonyms:N--L-β-phenylalanine ethyl ester

Chemical Property of N--L-β-phenylalanine ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of N--L-β-phenylalanine ethyl ester

There total 6 articles about N--L-β-phenylalanine ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

(L)-phenylalanine ethyl ester hydrochloride (3182-93-2) + Ac-N-carboxy α-dehydrophenylalanine anhydride (80465-38-9) → N--L-β-phenylalanine ethyl ester (118140-35-5)

Guidance literature:

With triethylamine; In tetrahydrofuran; Ambient temperature;

DOI:10.1248/cpb.32.3934

Reference yield: 98.0%

H-Phe-OEt (3081-24-1) + Ac-N-carboxy α-dehydrophenylalanine anhydride (80465-38-9) → N--L-β-phenylalanine ethyl ester (118140-35-5)

Guidance literature:

In tetrahydrofuran; for 0.666667h; Ambient temperature;

DOI:10.1246/cl.1981.1635

Reference yield:

H-Phe-OEt (3081-24-1) + (Z)-2-methyl-4-benzylideneoxazolin-5-one (41537-73-9) → N--L-β-phenylalanine ethyl ester (118140-35-5)

Guidance literature:

In 1,4-dioxane; for 24h;

DOI:10.1021/ja00301a025

upstream raw materials:

H-Phe-OEt

Ac-N-carboxy α-dehydrophenylalanine anhydride

(Z)-2-methyl-4-benzylideneoxazolin-5-one

(L)-phenylalanine ethyl ester hydrochloride

Downstream raw materials:

N-(α-acetylamino-cinnamoyl)-L-phenylalanine