diisopropyl-carbamic acid 4-hydroxy-6-phenyl-hex-1-enyl ester

Base Information

• Chemical Name: diisopropyl-carbamic acid 4-hydroxy-6-phenyl-hex-1-enyl ester
• CAS No.: 528869-38-7
• Molecular Formula: C₁₉H₂₉NO₃
• Molecular Weight: 319.444
• Mol file: 528869-38-7.mol

Synonyms:diisopropyl-carbamic acid 4-hydroxy-6-phenyl-hex-1-enyl ester

Chemical Property of diisopropyl-carbamic acid 4-hydroxy-6-phenyl-hex-1-enyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of diisopropyl-carbamic acid 4-hydroxy-6-phenyl-hex-1-enyl ester

There total 1 articles about diisopropyl-carbamic acid 4-hydroxy-6-phenyl-hex-1-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

3-phenyl-propionaldehyde (104-53-0) + N,N-Diisopropylcarbamidsaeure-(2-propenylester) (74562-19-9) → diisopropyl-carbamic acid 4-hydroxy-6-phenyl-hex-1-enyl ester (528869-38-7)

Guidance literature:

N,N-Diisopropylcarbamidsaeure-(2-propenylester); With n-butyllithium; (-)-sparteine; In hexane; toluene; at -78 ℃; for 2h;

With titanium(IV) isopropylate; In hexane; toluene; at -78 ℃; for 0.5h;

3-phenyl-propionaldehyde; In hexane; toluene; at -78 - -40 ℃; for 2h;

DOI:10.1021/ol034448r

Reference yield: 62.0%

triethylsilyl chloride (994-30-9) + diisopropyl-carbamic acid 4-hydroxy-6-phenyl-hex-1-enyl ester (528869-38-7) → (Z)-4-((3-ethylpentan-3-yl)oxy)-6-phenylhex-1-en-1-yl diisopropylcarbamate

Guidance literature:

With 1H-imidazole; In dichloromethane; at 0 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1039/C6OB02333A

Reference yield:

allyltributylstanane (24850-33-7) + diisopropyl-carbamic acid 4-hydroxy-6-phenyl-hex-1-enyl ester (528869-38-7) → 1-(2-phenethyl-cyclopropyl)-but-3-en-1-ol

Guidance literature:

allyltributylstanane; diisopropyl-carbamic acid 4-hydroxy-6-phenyl-hex-1-enyl ester; With 2,6-dimethylpyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at -78 - -10 ℃;

With lithium aluminium tetrahydride; In tetrahydrofuran; Heating;

DOI:10.1021/ol034448r

upstream raw materials:

3-phenyl-propionaldehyde

N,N-Diisopropylcarbamidsaeure-(2-propenylester)