6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-5(R)-(phenethyloxy)-1,2,3,4,4a(R),5,6,7,8,8a(R)-decahydronaphthyl-1(S)>ethyl>-4(R)-<(tert-butyldiphenylsilyl)oxy>-3,4,5,6-tetrahydro-2H-pyran-2-one

Base Information

Chemical Name:6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-5(R)-(phenethyloxy)-1,2,3,4,4a(R),5,6,7,8,8a(R)-decahydronaphthyl-1(S)>ethyl>-4(R)-<(tert-butyldiphenylsilyl)oxy>-3,4,5,6-tetrahydro-2H-pyran-2-one
CAS No.:127343-21-9
Molecular Formula:C₄₉H₆₈O₆Si
Molecular Weight:781.161
Hs Code.:

6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-5(R)-(phenethyloxy)-1,2,3,4,4a(R),5,6,7,8,8a(R)-decahydronaphthyl-1(S)>ethyl>-4(R)-<(tert-butyldiphenylsilyl)oxy>-3,4,5,6-tetrahydro-2H-pyran-2-one

Synonyms:6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-5(R)-(phenethyloxy)-1,2,3,4,4a(R),5,6,7,8,8a(R)-decahydronaphthyl-1(S)>ethyl>-4(R)-<(tert-butyldiphenylsilyl)oxy>-3,4,5,6-tetrahydro-2H-pyran-2-one

Suppliers and Price of 6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-5(R)-(phenethyloxy)-1,2,3,4,4a(R),5,6,7,8,8a(R)-decahydronaphthyl-1(S)>ethyl>-4(R)-<(tert-butyldiphenylsilyl)oxy>-3,4,5,6-tetrahydro-2H-pyran-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-5(R)-(phenethyloxy)-1,2,3,4,4a(R),5,6,7,8,8a(R)-decahydronaphthyl-1(S)>ethyl>-4(R)-<(tert-butyldiphenylsilyl)oxy>-3,4,5,6-tetrahydro-2H-pyran-2-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-5(R)-(phenethyloxy)-1,2,3,4,4a(R),5,6,7,8,8a(R)-decahydronaphthyl-1(S)>ethyl>-4(R)-<(tert-butyldiphenylsilyl)oxy>-3,4,5,6-tetrahydro-2H-pyran-2-one

There total 9 articles about 6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-5(R)-(phenethyloxy)-1,2,3,4,4a(R),5,6,7,8,8a(R)-decahydronaphthyl-1(S)>ethyl>-4(R)-<(tert-butyldiphenylsilyl)oxy>-3,4,5,6-tetrahydro-2H-pyran-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 127343-19-5
2,2-Dimethyl-butyric acid (1S,3R,4R,4aR,7S,8S,8aR)-8-{2-[(2R,4R)-4-(tert-butyl-diphenyl-silanyloxy)-6-oxo-tetrahydro-pyran-2-yl]-ethyl}-3,7-dimethyl-4-((E)-styryloxy)-decahydro-naphthalen-1-yl ester

: 127343-21-9
6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-5(R)-(phenethyloxy)-1,2,3,4,4a(R),5,6,7,8,8a(R)-decahydronaphthyl-1(S)>ethyl>-4(R)-<(tert-butyldiphenylsilyl)oxy>-3,4,5,6-tetrahydro-2H-pyran-2-one

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; at 25 ℃; for 8h; under 760 Torr; Yield given;
DOI:10.1021/jm00112a027

Reference yield:

: 4747-15-3
1-(2-methoxyvinyl)benzene

: 127343-21-9
6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-5(R)-(phenethyloxy)-1,2,3,4,4a(R),5,6,7,8,8a(R)-decahydronaphthyl-1(S)>ethyl>-4(R)-<(tert-butyldiphenylsilyl)oxy>-3,4,5,6-tetrahydro-2H-pyran-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: (+/-)-camphorsulfonic acid / CH₂Cl₂ / 3 h

2: H₂ / 10percent Pd/C / ethyl acetate / 8 h / 25 °C / 760 Torr

With camphor-10-sulfonic acid; hydrogen; palladium on activated charcoal; In dichloromethane; ethyl acetate;
DOI:10.1021/jm00112a027

Reference yield:

: 126453-95-0
6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-1,2,3,4,6,7,8,8a(R)-octahydronaphtyl-1(S)>ethyl>-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-one

: 127343-21-9
6(R)-<2-<8(S)-<(2,2-dimethylbutyryl)oxy>-2(S),6(R)-dimethyl-5(R)-(phenethyloxy)-1,2,3,4,4a(R),5,6,7,8,8a(R)-decahydronaphthyl-1(S)>ethyl>-4(R)-<(tert-butyldiphenylsilyl)oxy>-3,4,5,6-tetrahydro-2H-pyran-2-one

Guidance literature:: Multi-step reaction with 7 steps

1: imidazole / dimethylformamide / 4 h / 25 °C

2: N-bromosuccinimide, H₂O / tetrahydrofuran; dimethylsulfoxide / 1 h / 5 °C

3: pyridinium chlorochromate (PCC), 4 A sieves / CH₂Cl₂ / 1 h / 0 - 20 °C

4: Zn, acetic acid / tetrahydrofuran / 1 h / Ambient temperature

5: NaBH₄ / tetrahydrofuran; H₂O / 0.58 h / 0 °C

6: (+/-)-camphorsulfonic acid / CH₂Cl₂ / 3 h

7: H₂ / 10percent Pd/C / ethyl acetate / 8 h / 25 °C / 760 Torr

With 1H-imidazole; sodium tetrahydroborate; N-Bromosuccinimide; 4 A molecular sieve; camphor-10-sulfonic acid; water; hydrogen; acetic acid; pyridinium chlorochromate; zinc; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm00112a027