N-(diethoxyphosphoryl)-N',N''-bis(p-tolylsulfonyl)diethylenetriamine

Base Information

• Chemical Name: N-(diethoxyphosphoryl)-N',N''-bis(p-tolylsulfonyl)diethylenetriamine
• CAS No.: 134209-53-3
• Molecular Formula: C₂₂H₃₄N₃O₇PS₂
• Molecular Weight: 547.634
• Mol file: 134209-53-3.mol

Synonyms:N-(diethoxyphosphoryl)-N',N''-bis(p-tolylsulfonyl)diethylenetriamine

Chemical Property of N-(diethoxyphosphoryl)-N',N''-bis(p-tolylsulfonyl)diethylenetriamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(diethoxyphosphoryl)-N',N''-bis(p-tolylsulfonyl)diethylenetriamine

There total 3 articles about N-(diethoxyphosphoryl)-N',N''-bis(p-tolylsulfonyl)diethylenetriamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

diethyl chlorophosphate (814-49-3) + N,N'-bis(p-tolylsulfonyl)diethylenetriamine (134237-97-1) → N-(diethoxyphosphoryl)-N',N''-bis(p-tolylsulfonyl)diethylenetriamine (134209-53-3)

Guidance literature:

With triethylamine; In dichloromethane; for 1h; Ambient temperature;

DOI:10.1021/jo00016a018

Reference yield:

ditosylethylenediamine (4403-78-5) → N-(diethoxyphosphoryl)-N',N''-bis(p-tolylsulfonyl)diethylenetriamine (134209-53-3)

Guidance literature:

Multi-step reaction with 3 steps

1: NaH / DMF, 60 deg C, 1 h

2: 98 percent / borane-THF / tetrahydrofuran / 10 h / Heating

3: 100 percent / N(C₂H₅)3 / CH₂Cl₂ / 1 h / Ambient temperature

With borane-THF; sodium hydride; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1021/jo00016a018

Reference yield:

N-(cyanomethyl)-N,N'-bis(p-tolylsulfonyl)ethylenediamine (134209-56-6) → N-(diethoxyphosphoryl)-N',N''-bis(p-tolylsulfonyl)diethylenetriamine (134209-53-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / borane-THF / tetrahydrofuran / 10 h / Heating

2: 100 percent / N(C₂H₅)3 / CH₂Cl₂ / 1 h / Ambient temperature

With borane-THF; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1021/jo00016a018

upstream raw materials:

diethyl chlorophosphate

N,N'-bis(p-tolylsulfonyl)diethylenetriamine

ditosylethylenediamine

N-(cyanomethyl)-N,N'-bis(p-tolylsulfonyl)ethylenediamine

Downstream raw materials:

1,4,7,13,16-pentakis(p-tolylsulfonyl)-10,22-dioxa-1,4,7,13,16,19-hexaazacyclotetracosane hydrochloride

1-(diethoxyphosphoryl)-4,7,13,16,19-pentakis(p-tolylsulfonyl)-10,22,dioxa-1,4,7,13,16,19-hexaazacyclotetracosane