N-((2R,4aR,6R,7R,8S,8aS)-8-Allyloxy-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-acetamide

Base Information

Chemical Name:N-((2R,4aR,6R,7R,8S,8aS)-8-Allyloxy-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-acetamide
CAS No.:203435-10-3
Molecular Formula:C₂₅H₂₉NO₆
Molecular Weight:439.508
Hs Code.:

Synonyms:N-((2R,4aR,6R,7R,8S,8aS)-8-Allyloxy-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-acetamide

Suppliers and Price of N-((2R,4aR,6R,7R,8S,8aS)-8-Allyloxy-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-((2R,4aR,6R,7R,8S,8aS)-8-Allyloxy-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-acetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-((2R,4aR,6R,7R,8S,8aS)-8-Allyloxy-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-acetamide

There total 1 articles about N-((2R,4aR,6R,7R,8S,8aS)-8-Allyloxy-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 106-95-6
allyl bromide

: 176300-16-6
benzyl 2-acetamido-4,6-O-benzylidene-2-deoxy-β-D-allopyranoside

: 203435-10-3
N-((2R,4aR,6R,7R,8S,8aS)-8-Allyloxy-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-acetamide

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 5 min, 2.) DMF, room temperature, 1 h;
DOI:10.1021/jo971784a

Reference yield: 91.0%

: 203435-10-3
N-((2R,4aR,6R,7R,8S,8aS)-8-Allyloxy-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-acetamide

: 203435-11-4
N-((2R,3R,4S,5S,6R)-4-Allyloxy-2-benzyloxy-5-hydroxy-6-hydroxymethyl-tetrahydro-pyran-3-yl)-acetamide

Guidance literature:: With camphor-10-sulfonic acid; In methanol; at 60 ℃; for 1h;
DOI:10.1021/jo971784a

Reference yield:

: 203435-10-3
N-((2R,4aR,6R,7R,8S,8aS)-8-Allyloxy-6-benzyloxy-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl)-acetamide

: C₅₉H₅₅NO₁₆

Guidance literature:: Multi-step reaction with 3 steps

1: 91 percent / camphorsulfonic acid / methanol / 1 h / 60 °C

2: 91 percent / pyridine / CH₂Cl₂ / 1 h / -20 °C

3: 1.) molecular sieves 4A, 2.) trimethylsilyl triflate / 1.) CH₂Cl₂, room temperature, 30 min, 2.) CH₂Cl₂, room temperature

With pyridine; trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; camphor-10-sulfonic acid; In methanol; dichloromethane;
DOI:10.1021/jo971784a