di-(4-methylbenzyl) (Z,Z)-muconate

Base Information

• Chemical Name: di-(4-methylbenzyl) (Z,Z)-muconate
• CAS No.: 454647-03-1
• Molecular Formula: C₂₂H₂₂O₄
• Molecular Weight: 350.414
• Mol file: 454647-03-1.mol

Synonyms:di-(4-methylbenzyl) (Z,Z)-muconate

Chemical Property of di-(4-methylbenzyl) (Z,Z)-muconate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of di-(4-methylbenzyl) (Z,Z)-muconate

There total 3 articles about di-(4-methylbenzyl) (Z,Z)-muconate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methylbenzyl alcohol (589-18-4) + (Z,Z)-muconic acid dichloride (66415-44-9) → di-(4-methylbenzyl) (Z,Z)-muconate (454647-03-1)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃;

DOI:10.1021/ja0205333

Reference yield:

cis,cis-Muconic acid (1119-72-8) → di-(4-methylbenzyl) (Z,Z)-muconate (454647-03-1)

Guidance literature:

Multi-step reaction with 2 steps

1: thionyl chloride; N,N-dimethylformamide / CH₂Cl₂ / 5 h / Heating

2: Et₃N / CH₂Cl₂ / 20 °C

With thionyl chloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;

DOI:10.1021/ja0205333

Reference yield:

cis,cis-Muconic acid (1119-72-8) + 4-Methylbenzyl bromide (104-81-4) → di-(4-methylbenzyl) (Z,Z)-muconate (454647-03-1)

Guidance literature:

With potassium carbonate; In N,N,N,N,N,N-hexamethylphosphoric triamide; at 20 ℃;

DOI:10.1080/15421400590958539

upstream raw materials:

4-Methylbenzyl alcohol

(Z,Z)-muconic acid dichloride

cis,cis-Muconic acid

4-Methylbenzyl bromide