methyl (2E)-3-(4-{[2-{[(5-methyl-2-furyl)sulfonyl]amino}-5-(trifluoromethyl)phenoxy]methyl}phenyl)acrylate

Base Information

Chemical Name:methyl (2E)-3-(4-{[2-{[(5-methyl-2-furyl)sulfonyl]amino}-5-(trifluoromethyl)phenoxy]methyl}phenyl)acrylate
CAS No.:913078-89-4
Molecular Formula:C₂₃H₂₀F₃NO₆S
Molecular Weight:495.476
Hs Code.:

Synonyms:methyl (2E)-3-(4-{[2-{[(5-methyl-2-furyl)sulfonyl]amino}-5-(trifluoromethyl)phenoxy]methyl}phenyl)acrylate

Suppliers and Price of methyl (2E)-3-(4-{[2-{[(5-methyl-2-furyl)sulfonyl]amino}-5-(trifluoromethyl)phenoxy]methyl}phenyl)acrylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl (2E)-3-(4-{[2-{[(5-methyl-2-furyl)sulfonyl]amino}-5-(trifluoromethyl)phenoxy]methyl}phenyl)acrylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl (2E)-3-(4-{[2-{[(5-methyl-2-furyl)sulfonyl]amino}-5-(trifluoromethyl)phenoxy]methyl}phenyl)acrylate

There total 10 articles about methyl (2E)-3-(4-{[2-{[(5-methyl-2-furyl)sulfonyl]amino}-5-(trifluoromethyl)phenoxy]methyl}phenyl)acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 69815-95-8
5-methylfuran-2-sulfonyl chloride

: 913078-87-2
methyl (2E)-3-(4-{[2-amino-5-(trifluoromethyl)phenoxy]methyl}phenyl)acrylate

: 913078-89-4
methyl (2E)-3-(4-{[2-{[(5-methyl-2-furyl)sulfonyl]amino}-5-(trifluoromethyl)phenoxy]methyl}phenyl)acrylate

Guidance literature:: With pyridine; In dichloromethane; for 9h;
DOI:10.1016/j.bmc.2006.06.067

Reference yield:

: 534-22-5
2-methylfuran

: 913078-89-4
methyl (2E)-3-(4-{[2-{[(5-methyl-2-furyl)sulfonyl]amino}-5-(trifluoromethyl)phenoxy]methyl}phenyl)acrylate

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / acetonitrile / 23 h / 40 °C

2: 41 percent / oxalyl chloride / 1,2-dimethoxy-ethane; dimethylformamide / 3 h / 20 °C

3: 80 percent / pyridine / CH₂Cl₂ / 9 h

With pyridine; oxalyl dichloride; In 1,2-dimethoxyethane; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/j.bmc.2006.06.067

Reference yield:

: 907587-46-6
methyl 4-[(2-nitro-5-(trifluoromethyl)phenoxy)methyl]benzoate

: 913078-89-4
methyl (2E)-3-(4-{[2-{[(5-methyl-2-furyl)sulfonyl]amino}-5-(trifluoromethyl)phenoxy]methyl}phenyl)acrylate

Guidance literature:: Multi-step reaction with 6 steps

1: 85 percent / lithium borohydride / diethyl ether; methanol / Heating

2: 81 percent / dimethylsulfoxide; sulfur trioxide pyridine complex; diisopropylethylamine / ethyl acetate / 0.5 h

3: 90 percent / piperidine; pyridine / 0.5 h / 100 °C

4: 100 percent / potassium carbonate / dimethylformamide / 1.5 h / 65 °C

5: 91 percent / iron; acetic acid / H₂O / 0.5 h / 50 °C

6: 80 percent / pyridine / CH₂Cl₂ / 9 h

With piperidine; pyridine; lithium borohydride; sulfur trioxide pyridine complex; iron; potassium carbonate; acetic acid; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; In methanol; diethyl ether; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2006.06.067