3'-O-(tert-butyldimethylsilyl)-5'-(3,3,3-triphenylpropanamide)-5'-deoxythymidine

Base Information

Chemical Name:3'-O-(tert-butyldimethylsilyl)-5'-(3,3,3-triphenylpropanamide)-5'-deoxythymidine
CAS No.:1257404-35-5
Molecular Formula:C₃₇H₄₅N₃O₅Si
Molecular Weight:639.867
Hs Code.:

Synonyms:3'-O-(tert-butyldimethylsilyl)-5'-(3,3,3-triphenylpropanamide)-5'-deoxythymidine

Suppliers and Price of 3'-O-(tert-butyldimethylsilyl)-5'-(3,3,3-triphenylpropanamide)-5'-deoxythymidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3'-O-(tert-butyldimethylsilyl)-5'-(3,3,3-triphenylpropanamide)-5'-deoxythymidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3'-O-(tert-butyldimethylsilyl)-5'-(3,3,3-triphenylpropanamide)-5'-deoxythymidine

There total 4 articles about 3'-O-(tert-butyldimethylsilyl)-5'-(3,3,3-triphenylpropanamide)-5'-deoxythymidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 900-91-4
3,3,3-triphenylpropionic acid

: 130128-70-0
5'-amino-3'-O-(tert-butyldimethylsilyl)-5’-deoxythymidine

: 1257404-35-5
3'-O-(tert-butyldimethylsilyl)-5'-(3,3,3-triphenylpropanamide)-5'-deoxythymidine

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1002/cmdc.201300129

Reference yield:

: 1257404-34-4
5'-(1,3-dihydro-1,3-dioxo-4,5,6,7-tetrachloroisoindol-2-yl)-3'-O-(tert-butyldimethylsilyl)-5'-deoxythymidine

: 1257404-35-5
3'-O-(tert-butyldimethylsilyl)-5'-(3,3,3-triphenylpropanamide)-5'-deoxythymidine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 1 h / Reflux

2: triethylamine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / dichloromethane / 20 °C

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; hydrazine hydrate; triethylamine; In ethanol; dichloromethane;
DOI:10.1002/cmdc.201300129

Reference yield:

: 210490-66-7
4,5,6,7-Tetrachloro-2-[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl]-isoindole-1,3-dione

: 1257404-35-5
3'-O-(tert-butyldimethylsilyl)-5'-(3,3,3-triphenylpropanamide)-5'-deoxythymidine

Guidance literature:: Multi-step reaction with 3 steps

1: 1H-imidazole / N,N-dimethyl-formamide / 20 °C

2: hydrazine hydrate / ethanol / 1 h / Reflux

3: triethylamine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / dichloromethane / 20 °C

With 1H-imidazole; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; hydrazine hydrate; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1002/cmdc.201300129