C₃₆H₄₃F₅OSi

Base Information

• Chemical Name: C₃₆H₄₃F₅OSi
• CAS No.: 221342-64-9
• Molecular Formula: C₃₆H₄₃F₅OSi
• Molecular Weight: 614.814
• Mol file: 221342-64-9.mol

Synonyms:C₃₆H₄₃F₅OSi

Chemical Property of C₃₆H₄₃F₅OSi

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₆H₄₃F₅OSi

There total 15 articles about C₃₆H₄₃F₅OSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

C36H44F4O2Si (221342-63-8) → C36H43F5OSi (221342-64-9)

Guidance literature:

With 4,4'-diaminostilbene-2,2'-disulfonic acid; In toluene; at -70 - -60 ℃;

DOI:10.1002/(SICI)1521-3773(19991115)38:22<3373::AID-ANIE3373>3.0.CO;2-F

Reference yield:

spiro[3.5]nonane-6,8-dione (221342-48-9) → C36H43F5OSi (221342-64-9)

Guidance literature:

Multi-step reaction with 7 steps

1.1: isobutanol; p-TsOH / toluene / Heating

1.2: 77 percent / RedAl / toluene / 40 - 50 °C

2.1: 42 percent / TiCl₄; Ti(i-PrO)4 / CH₂Cl₂ / 2.17 h / -7 - 20 °C

3.1: SOCl₂; pyridine / 0 °C

3.2: NCS; (PhCO₂)2 / CH₂Cl₂ / 20 °C

3.3: DBU / dioxane / 96 °C

4.1: 78 percent / (1R,2S)-1-aminoindan-2-ol; BH₃; PhNEt₂ / tetrahydrofuran / 20 °C

5.1: 80 percent / NEt₃; DMAP / dimethylformamide / 70 °C

6.1: 55 percent / LiAlH₄ / tetrahydrofuran / 0 - 20 °C

7.1: 75 percent / DAST / toluene / -70 - -60 °C

With pyridine; titanium(IV) isopropylate; dmap; lithium aluminium tetrahydride; thionyl chloride; 2-methyl-propan-1-ol; (1R,2S)-1-Amino-2-indanol; borane; titanium tetrachloride; toluene-4-sulfonic acid; triethylamine; 4,4'-diaminostilbene-2,2'-disulfonic acid; N,N-diethylaniline; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene; 1.1: Etherification / 1.2: Reduction / 2.1: Cyclization / 3.1: Dehydration / 3.2: Chlorination / 3.3: Aromatisation / 4.1: Reduction / 5.1: Etherification / 6.1: Reduction / 7.1: Substitution;

DOI:10.1002/(SICI)1521-3773(19991115)38:22<3373::AID-ANIE3373>3.0.CO;2-F

Reference yield:

2-(trimethylsilyloxy)-3-methyl-1-butene (17510-45-1) → C36H43F5OSi (221342-64-9)

Guidance literature:

Multi-step reaction with 6 steps

1.1: TiCl₄; Ti(OiPr)4 / CH₂Cl₂

1.2: 65 percent / CH₂Cl₂

2.1: SOCl₂; pyridine

2.2: NCS; (PhCO₂)2 / CH₂Cl₂

2.3: DBU; air / dioxane

3.1: BH₃*Et₂NPh; (1R,2S)-1-aminoindanol

4.1: dimethylformamide

5.1: LAH / tetrahydrofuran

6.1: DAST

With pyridine; titanium(IV) isopropylate; lithium aluminium tetrahydride; borane N,N-diethylaniline complex; thionyl chloride; (1R,2S)-1-Amino-2-indanol; titanium tetrachloride; 4,4'-diaminostilbene-2,2'-disulfonic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; 1.1: Mukaiyama-Michael addition / 1.2: Michael addition;

DOI:10.2533/000942904777678082

upstream raw materials:

C₃₆H₄₄F₄O₂Si

C₃₆H₄₄F₄O₂Si

2-(trimethylsilyloxy)-3-methyl-1-butene

spiro[3.5]non-7-en-6-one