Technology Process of 6-bromo-2-(chloromethyl)-3-phenyl-3H-imidazo[4,5-b]pyridine
There total 4 articles about 6-bromo-2-(chloromethyl)-3-phenyl-3H-imidazo[4,5-b]pyridine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
dichloromethane;
at 30 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: triethylamine / dimethyl sulfoxide / 80 °C
2: ammonium chloride; sodium sulfide nonahydrate / methanol / 2 h / Reflux
3: toluene-4-sulfonic acid / dichloromethane / 1 h / 30 °C
With
sodium sulfide nonahydrate; ammonium chloride; toluene-4-sulfonic acid; triethylamine;
In
methanol; dichloromethane; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: ammonium chloride; sodium sulfide nonahydrate / methanol / 2 h / Reflux
2: toluene-4-sulfonic acid / dichloromethane / 1 h / 30 °C
With
sodium sulfide nonahydrate; ammonium chloride; toluene-4-sulfonic acid;
In
methanol; dichloromethane;