methyl 1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate

Base Information

• Chemical Name: methyl 1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate
• CAS No.: 437606-07-0
• Molecular Formula: C₁₇H₂₈N₂O₅
• Molecular Weight: 340.42
• Mol file: 437606-07-0.mol

Synonyms:methyl 1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate

Chemical Property of methyl 1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate

There total 4 articles about methyl 1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methyl 3-benzyloxycarbonyl-1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate (459454-23-0) → methyl 1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate (437606-07-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 6h;

DOI:10.1023/A:1015061620557

Reference yield:

menthoxyacetic acid (40248-63-3) → methyl 1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate (437606-07-0)

Guidance literature:

Multi-step reaction with 3 steps

1: SOCl₂ / 1,2-dichloro-ethane / 5 h / Heating

2: 65 percent / DMAP; pyridine / CH₂Cl₂ / 24 h / Heating

3: 95 percent / H₂ / 10 percent Pd/C / ethyl acetate / 6 h

With pyridine; dmap; thionyl chloride; hydrogen; palladium on activated charcoal; In dichloromethane; ethyl acetate; 1,2-dichloro-ethane;

DOI:10.1023/A:1015061620557

Reference yield:

L-menthoxyacetyl chloride (15356-62-4) → methyl 1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate (437606-07-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 65 percent / DMAP; pyridine / CH₂Cl₂ / 24 h / Heating

2: 95 percent / H₂ / 10 percent Pd/C / ethyl acetate / 6 h

With pyridine; dmap; hydrogen; palladium on activated charcoal; In dichloromethane; ethyl acetate;

DOI:10.1023/A:1015061620557

upstream raw materials:

methyl 3-benzyloxycarbonyl-1-(d-menthoxyacetyl)-2-oxoimidazolidine-4(S)-carboxylate

menthoxyacetic acid

L-menthoxyacetyl chloride

methyl 3-benzyloxycarbonyl-2-oxo-imidazolidine-4(S)-carboxylate