Acetic acid 2-hydroxy-2-phenylsulfanylmethyl-pent-4-enyl ester

Base Information

• Chemical Name: Acetic acid 2-hydroxy-2-phenylsulfanylmethyl-pent-4-enyl ester
• CAS No.: 159002-92-3
• Molecular Formula: C₁₄H₁₈O₃S
• Molecular Weight: 266.361
• Mol file: 159002-92-3.mol

Synonyms:Acetic acid 2-hydroxy-2-phenylsulfanylmethyl-pent-4-enyl ester

Chemical Property of Acetic acid 2-hydroxy-2-phenylsulfanylmethyl-pent-4-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Acetic acid 2-hydroxy-2-phenylsulfanylmethyl-pent-4-enyl ester

There total 1 articles about Acetic acid 2-hydroxy-2-phenylsulfanylmethyl-pent-4-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

acetate of 1-hydroxy-3-phenylthio-2-propanone (22198-57-8) + allyl bromide (106-95-6) → Acetic acid 2-hydroxy-2-phenylsulfanylmethyl-pent-4-enyl ester (159002-92-3)

Guidance literature:

With aluminium; tin(ll) chloride; In tetrahydrofuran; water; Ambient temperature;

DOI:10.1016/S0040-4039(00)60531-2

Reference yield: 100.0%

Acetic acid 2-hydroxy-2-phenylsulfanylmethyl-pent-4-enyl ester (159002-92-3) → 2-Phenylsulfanylmethyl-pent-4-ene-1,2-diol (159099-54-4)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; water; Ambient temperature;

DOI:10.1016/S0040-4039(00)60531-2

Reference yield:

Acetic acid 2-hydroxy-2-phenylsulfanylmethyl-pent-4-enyl ester (159002-92-3) → 2-Allyl-2-(4-methoxy-benzyl)-oxirane (159002-94-5)

Guidance literature:

Multi-step reaction with 5 steps

1: 100 percent / LiOH / tetrahydrofuran; H₂O / Ambient temperature

2: pyridine / CH₂Cl₂ / Ambient temperature

3: NaOH / methanol / -10 °C

4: 86 percent / CuI, Me₂S / tetrahydrofuran / -15 °C

5: 1) Et₃OBF₄, 2) aq.NaOH / 1) CH₂Cl₂, 2) 0 deg C

With pyridine; lithium hydroxide; sodium hydroxide; copper(l) iodide; dimethylsulfide; triethyloxonium fluoroborate; In tetrahydrofuran; methanol; dichloromethane; water;

DOI:10.1016/S0040-4039(00)60531-2

upstream raw materials:

acetate of 1-hydroxy-3-phenylthio-2-propanone

allyl bromide

Downstream raw materials:

2-Phenylsulfanylmethyl-pent-4-ene-1,2-diol

2-Allyl-2-(4-methoxy-benzyl)-oxirane

1-(4-Methoxy-phenyl)-2-phenylsulfanylmethyl-pent-4-en-2-ol

2-Allyl-2-phenylsulfanylmethyl-oxirane