(2R,3R)-2,3-bis(tert-butyldimethylsilyloxy)-4-(p-methoxybenzyloxy)butyl pivalate

Base Information

Chemical Name:(2R,3R)-2,3-bis(tert-butyldimethylsilyloxy)-4-(p-methoxybenzyloxy)butyl pivalate
CAS No.:870680-66-3
Molecular Formula:C₂₉H₅₄O₆Si₂
Molecular Weight:554.915
Hs Code.:

Synonyms:(2R,3R)-2,3-bis(tert-butyldimethylsilyloxy)-4-(p-methoxybenzyloxy)butyl pivalate

Suppliers and Price of (2R,3R)-2,3-bis(tert-butyldimethylsilyloxy)-4-(p-methoxybenzyloxy)butyl pivalate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2R,3R)-2,3-bis(tert-butyldimethylsilyloxy)-4-(p-methoxybenzyloxy)butyl pivalate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2R,3R)-2,3-bis(tert-butyldimethylsilyloxy)-4-(p-methoxybenzyloxy)butyl pivalate

There total 6 articles about (2R,3R)-2,3-bis(tert-butyldimethylsilyloxy)-4-(p-methoxybenzyloxy)butyl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 870680-65-2
(2R,3R)-1-pivaloxy-4-(p-methoxybenzyloxy)-2,3-butanediol

: 69739-34-0
t-butyldimethylsiyl triflate

: 870680-66-3
(2R,3R)-2,3-bis(tert-butyldimethylsilyloxy)-4-(p-methoxybenzyloxy)butyl pivalate

Guidance literature:: With triethylamine; In dichloromethane; at 0 ℃; for 0.5h;
DOI:10.1021/ol0523493

Reference yield:

: 870680-64-1
(E)-4-(p-methoxybenzyloxy)-2-butenyl pivalate

: 870680-66-3
(2R,3R)-2,3-bis(tert-butyldimethylsilyloxy)-4-(p-methoxybenzyloxy)butyl pivalate

Guidance literature:: Multi-step reaction with 2 steps

1: 0.066 g / AD-mix-α; methanesulfonamide; H2O / 2-methyl-propan-2-ol / 0 - 20 °C

2: Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

With AD-mix-α; methanesulfonamide; water; triethylamine; In dichloromethane; tert-butyl alcohol; 1: Sharpless dihydroxylation;
DOI:10.1021/ol0523493

Reference yield:

: 143833-81-2
(Z)-4-(4-methoxybenzyloxy)but-2-en-1-ol

: 870680-66-3
(2R,3R)-2,3-bis(tert-butyldimethylsilyloxy)-4-(p-methoxybenzyloxy)butyl pivalate

Guidance literature:: Multi-step reaction with 5 steps

1: 4 Angstroem molecular sieves; PCC / CH₂Cl₂ / 48 h / 20 °C

2: DIBAL-H / CH₂Cl₂; hexane / 0.5 h / -78 °C

3: pyridine; DMAP / 0.5 h / 25 °C

4: 0.066 g / AD-mix-α; methanesulfonamide; H2O / 2-methyl-propan-2-ol / 0 - 20 °C

5: Et₃N / CH₂Cl₂ / 0.5 h / 0 °C

With pyridine; dmap; AD-mix-α; methanesulfonamide; 4 A molecular sieve; water; diisobutylaluminium hydride; triethylamine; pyridinium chlorochromate; In hexane; dichloromethane; tert-butyl alcohol; 4: Sharpless dihydroxylation;
DOI:10.1021/ol0523493