143833-81-2

Basic information

• Product Name: 2-Buten-1-ol, 4-[(4-methoxyphenyl)methoxy]-, (2Z)-
• CAS NO: 143833-81-2
• Molecular Formula: C12H16O3
• Molecular Weight: 208.257
• Mol File: 143833-81-2.mol
• Article Data: 23

Chemical Properties

• CAS DataBase Reference: 2-Buten-1-ol, 4-[(4-methoxyphenyl)methoxy]-, (2Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Buten-1-ol, 4-[(4-methoxyphenyl)methoxy]-, (2Z)-(143833-81-2)
• EPA Substance Registry System: 2-Buten-1-ol, 4-[(4-methoxyphenyl)methoxy]-, (2Z)-(143833-81-2)

Safety Data

• Hazardous Substances Data: 143833-81-2(Hazardous Substances Data)

Upstream product

• 91202-69-6 (Z)-4-(tert-butyldimethylsilyloxy)but-2-en-1-ol 
• 105-13-5 4-Methoxybenzyl alcohol 
• 6117-80-2 1,4-butenediol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 89238-99-3 O-(4-methoxybenzyl)-trichloroacetimidate 
• 123-11-5 4-methoxy-benzaldehyde 
• 824-94-2 p-methoxybenzyl chloride 
• 74076-63-4 2-(4-methoxyphenyl)-4,7-dihydro-1,3-dioxepine 

Downstream Products

• 143833-82-3 (2R,3S)-2,3-epoxy-4-O-(4-methoxybenzyl)butan-1,4-diol 
• 1394138-33-0 (Z)-4-(4-methoxybenzyloxy)but-2-enyl acetate 

Relevant articles and documents

One-pot oxidation/isomerization of Z-allylic alcohols with oxygen as stoichiometric oxidant

A method for generating (E)-α,β-unsaturated aldehydes from Z-allylic alcohols or E/Z-mixtures is described. The one-pot procedure involves a Cu-catalyzed oxidation followed by an organocatalytic Z/E-isomerization with N,N-dimethylaminopyridine (DMAP).

Alkyne Aminopalladation/Heck and Suzuki Cascades: An Approach to Tetrasubstituted Enamines

Alkyne aminopalladation reactions starting from tosylamides are reported. The emerging vinylic Pd species are converted either in an intramolecular Heck reaction with olefinic units or in an intermolecular Suzuki reaction by using boronic acids exhibiting broad functional group tolerance. Tetra(hetero)substituted tosylated enamines are obtained in a simple one-pot process.

Sulfated tungstate as hydroxyl group activator for preparation of benzyl, including p-methoxybenzyl ethers of alcohols and phenols

Sulfated tungstate was found to be an effective heterogeneous and reusable catalyst for hydroxy group activation–mediated preparation of benzylic ethers including p-methoxybenzylic ethers of a wide range of alcohols and phenols under mild reaction conditions.

A very practical and selective method for PMB protection of alcohols

A very simple, practical and efficient one-step heterogeneous protocol for the PMB protection of alcohols using Amberlyst-15 has been developed. The stability and hazard issues regarding PMBCl and PMBBr are totally avoided by directly using anisyl alcohol for the protection. Alcohols are protected in very good yields. The selective mono-PMB protection of diols as well as di-PMB protection of diols was achieved in good yields, along with the demonstration of recyclability of the catalyst.