1-(4-tert-butylphenyl)-2-(triphenylphosphosphanylidene)ethanone

Base Information

• Chemical Name: 1-(4-tert-butylphenyl)-2-(triphenylphosphosphanylidene)ethanone
• CAS No.: 1422452-72-9
• Molecular Formula: C₃₀H₂₉OP
• Molecular Weight: 436.533
• Mol file: 1422452-72-9.mol

Synonyms:1-(4-tert-butylphenyl)-2-(triphenylphosphosphanylidene)ethanone

Chemical Property of 1-(4-tert-butylphenyl)-2-(triphenylphosphosphanylidene)ethanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-tert-butylphenyl)-2-(triphenylphosphosphanylidene)ethanone

There total 2 articles about 1-(4-tert-butylphenyl)-2-(triphenylphosphosphanylidene)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C30H30OP(1+)*Br(1-) → 1-(4-tert-butylphenyl)-2-(triphenylphosphosphanylidene)ethanone (1422452-72-9)

Guidance literature:

With sodium hydroxide; In methanol; water; for 5h; pH=7 - 8;

DOI:10.1016/j.ejmech.2012.11.007

Reference yield:

2-bromo-1-(4-(tert-butyl)phenyl)ethanone (30095-47-7) + triphenylphosphine (603-35-0) → 1-(4-tert-butylphenyl)-2-(triphenylphosphosphanylidene)ethanone (1422452-72-9)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / Inert atmosphere

2: sodium hydroxide / methanol; water / 5 h / pH 7 - 8

With sodium hydroxide; In methanol; dichloromethane; water;

DOI:10.1016/j.ejmech.2012.11.007

Reference yield: 91.0%

1-(4-tert-butylphenyl)-2-(triphenylphosphosphanylidene)ethanone (1422452-72-9) + (2-formyl-5-methoxyphenyl)boronic acid (40138-18-9) → C20H23BO4

Guidance literature:

With C₄₄H₄₈N₆O₄; In chlorobenzene; at 20 ℃; for 37h; enantioselective reaction;

DOI:10.1039/c6sc04522g

upstream raw materials:

2-bromo-1-(4-(tert-butyl)phenyl)ethanone

triphenylphosphine

Downstream raw materials:

(E)-3-(3-(4-tert-butylphenyl)-3-oxoprop-1-enyl)-5-(cyclohexylmethoxy)-4H-chromen-4-one

(E)-3-(3-(4-tert-butylphenyl)-3-hydroxyprop-1-enyl)-5-(cyclohexylmethoxy)-4H-chromen-4-one