(S)-(-)-ethyl 4-(t-butyldiphenylsilyloxy)-4-(4-propylfuran-3-yl)butyrate

Base Information

Chemical Name:(S)-(-)-ethyl 4-(t-butyldiphenylsilyloxy)-4-(4-propylfuran-3-yl)butyrate
CAS No.:1454573-57-9
Molecular Formula:C₂₉H₃₈O₄Si
Molecular Weight:478.704
Hs Code.:

Synonyms:(S)-(-)-ethyl 4-(t-butyldiphenylsilyloxy)-4-(4-propylfuran-3-yl)butyrate

Suppliers and Price of (S)-(-)-ethyl 4-(t-butyldiphenylsilyloxy)-4-(4-propylfuran-3-yl)butyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-(-)-ethyl 4-(t-butyldiphenylsilyloxy)-4-(4-propylfuran-3-yl)butyrate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-(-)-ethyl 4-(t-butyldiphenylsilyloxy)-4-(4-propylfuran-3-yl)butyrate

There total 6 articles about (S)-(-)-ethyl 4-(t-butyldiphenylsilyloxy)-4-(4-propylfuran-3-yl)butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 20662-89-9
4-phenyl-1,3-oxazole

: 1454573-53-5
(S)-(-)-ethyl 4-(t-butyldiphenylsilyloxy)-non-5-ynoate

: 1454573-57-9
(S)-(-)-ethyl 4-(t-butyldiphenylsilyloxy)-4-(4-propylfuran-3-yl)butyrate

Guidance literature:: With hydroquinone; at 260 - 270 ℃; for 20h; Sealed tube; Inert atmosphere; Darkness;
DOI:10.1021/ol402345x

Reference yield:

: 86650-50-2
1-pentynylzinc chloride

: 1454573-57-9
(S)-(-)-ethyl 4-(t-butyldiphenylsilyloxy)-4-(4-propylfuran-3-yl)butyrate

Guidance literature:: Multi-step reaction with 4 steps

1: tetrahydrofuran; hexane / -78 - 20 °C / Inert atmosphere

2: (1S,2S)-(+)-N-tosyl-1,2-diphenylethane-1,2-diamine[η6-1-isopropyl-4-methylbenzene]-ruthenium(II) / dichloromethane; isopropyl alcohol / 15 h / 20 °C / Inert atmosphere

3: dmap; 1H-imidazole / N,N-dimethyl-formamide / 2 h / 20 °C

4: hydroquinone / 20 h / 260 - 270 °C / Sealed tube; Inert atmosphere; Darkness

With 1H-imidazole; dmap; (1S,2S)-(+)-N-tosyl-1,2-diphenylethane-1,2-diamine[η6-1-isopropyl-4-methylbenzene]-ruthenium(II); hydroquinone; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/ol402345x

Reference yield:

: 627-19-0
1-Pentyne

: 1454573-57-9
(S)-(-)-ethyl 4-(t-butyldiphenylsilyloxy)-4-(4-propylfuran-3-yl)butyrate

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -78 °C / Inert atmosphere

1.2: 0.5 h / -78 °C / Inert atmosphere

2.1: tetrahydrofuran; hexane / -78 - 20 °C / Inert atmosphere

3.1: (1S,2S)-(+)-N-tosyl-1,2-diphenylethane-1,2-diamine[η6-1-isopropyl-4-methylbenzene]-ruthenium(II) / dichloromethane; isopropyl alcohol / 15 h / 20 °C / Inert atmosphere

4.1: dmap; 1H-imidazole / N,N-dimethyl-formamide / 2 h / 20 °C

5.1: hydroquinone / 20 h / 260 - 270 °C / Sealed tube; Inert atmosphere; Darkness

With 1H-imidazole; dmap; (1S,2S)-(+)-N-tosyl-1,2-diphenylethane-1,2-diamine[η6-1-isopropyl-4-methylbenzene]-ruthenium(II); n-butyllithium; hydroquinone; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/ol402345x