Technology Process of C42H51N4O10P
There total 11 articles about C42H51N4O10P which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at 0 - 20 ℃;
Inert atmosphere;
DOI:10.1021/ol401566r
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 2,6-dimethylpyridine / dichloromethane / 1 h / 0 °C / Inert atmosphere
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere
3: pyridine / 1 h / 0 °C / Inert atmosphere
4: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C / Inert atmosphere
5: 20% palladium hydroxide-activated charcoal; cyclohexene / ethanol / Reflux; Inert atmosphere
6: pyridine / 0 - 20 °C / Inert atmosphere
7: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C / Inert atmosphere
With
pyridine; 2,6-dimethylpyridine; 20% palladium hydroxide-activated charcoal; tetrabutyl ammonium fluoride; sodium hydride; N-ethyl-N,N-diisopropylamine; cyclohexene;
In
tetrahydrofuran; ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/ol401566r
- Guidance literature:
-
Multi-step reaction with 5 steps
1: pyridine / 1 h / 0 °C / Inert atmosphere
2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 - 20 °C / Inert atmosphere
3: 20% palladium hydroxide-activated charcoal; cyclohexene / ethanol / Reflux; Inert atmosphere
4: pyridine / 0 - 20 °C / Inert atmosphere
5: N-ethyl-N,N-diisopropylamine / dichloromethane / 0 - 20 °C / Inert atmosphere
With
pyridine; 20% palladium hydroxide-activated charcoal; sodium hydride; N-ethyl-N,N-diisopropylamine; cyclohexene;
In
ethanol; dichloromethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/ol401566r