erythro-trans-1-Benzyl-2-methoxycarbonyl-3-methyl-aziridin

Base Information

Chemical Name:erythro-trans-1-Benzyl-2-methoxycarbonyl-3-methyl-aziridin
CAS No.:173143-75-4
Molecular Formula:C₁₂H₁₅NO₂
Molecular Weight:205.257
Hs Code.:

Synonyms:erythro-trans-1-Benzyl-2-methoxycarbonyl-3-methyl-aziridin

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of erythro-trans-1-Benzyl-2-methoxycarbonyl-3-methyl-aziridin

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Technology Process of erythro-trans-1-Benzyl-2-methoxycarbonyl-3-methyl-aziridin

There total 4 articles about erythro-trans-1-Benzyl-2-methoxycarbonyl-3-methyl-aziridin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 196862-32-5
methyl (2S,3R)-2-(benzylamino)-3-hydroxybutanoate

: 173143-75-4
(2S,3S)-1-Benzyl-3-methyl-aziridine-2-carboxylic acid methyl ester

Guidance literature:: With tetrachloromethane; triphenylphosphine; In acetonitrile; at 25 ℃; for 16h;
DOI:10.1039/a806236f

Reference yield: 67.0%

: 196862-32-5
methyl (2S,3R)-2-(benzylamino)-3-hydroxybutanoate

: 173143-75-4
erythro-trans-1-Benzyl-2-methoxycarbonyl-3-methyl-aziridin

Guidance literature:: With triethylamine; triphenylphosphine; In tetrachloromethane; acetonitrile; Ambient temperature;
DOI:10.1021/jo970918h

Reference yield:

: 100-52-7
benzaldehyde

: 173143-75-4
erythro-trans-1-Benzyl-2-methoxycarbonyl-3-methyl-aziridin

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) Et₃N, 2.) NaBH₄ / 1) MeOH, 0 deg C

2: 67 percent / PPh₃, Et₃N / CCl₄; acetonitrile / Ambient temperature

With sodium tetrahydroborate; triethylamine; triphenylphosphine; In tetrachloromethane; acetonitrile;
DOI:10.1021/jo970918h