(E)-2-(5-fluoro-1-(4-(methylthio)benzylidene)-1H-inden-3-yl)-N-tosylacetamide

Base Information

• Chemical Name: (E)-2-(5-fluoro-1-(4-(methylthio)benzylidene)-1H-inden-3-yl)-N-tosylacetamide
• CAS No.: 1361001-27-5
• Molecular Formula: C₂₆H₂₂FNO₃S₂
• Molecular Weight: 479.596

Synonyms:(E)-2-(5-fluoro-1-(4-(methylthio)benzylidene)-1H-inden-3-yl)-N-tosylacetamide

Chemical Property of (E)-2-(5-fluoro-1-(4-(methylthio)benzylidene)-1H-inden-3-yl)-N-tosylacetamide

Chemical Property:

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Technology Process of (E)-2-(5-fluoro-1-(4-(methylthio)benzylidene)-1H-inden-3-yl)-N-tosylacetamide

There total 1 articles about (E)-2-(5-fluoro-1-(4-(methylthio)benzylidene)-1H-inden-3-yl)-N-tosylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

(E)-2-(5-fluoro-1-(4-(methylthio)benzylidene)-1H-inden-3-yl)acetic acid + toluene-4-sulfonamide (70-55-3) → (E)-2-(5-fluoro-1-(4-(methylthio)benzylidene)-1H-inden-3-yl)-N-tosylacetamide (1361001-27-5)

Guidance literature:

(E)-2-(5-fluoro-1-(4-(methylthio)benzylidene)-1H-inden-3-yl)acetic acid; With 1,1'-carbonyldiimidazole; In dichloromethane; at 0 - 5 ℃; for 2h; Inert atmosphere;

toluene-4-sulfonamide; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; for 20h; Inert atmosphere;

DOI:10.1021/jm201528b

upstream raw materials:

toluene-4-sulfonamide

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