Tetrakis(4-N-methylpyridyl)porphine

Base Information

• Chemical Name: Tetrakis(4-N-methylpyridyl)porphine
• CAS No.: 38673-65-3
• Molecular Formula: C44H38N8+4
• Molecular Weight: 678.82612
• Mol file: 38673-65-3.mol

Synonyms:tmpyp4;Tetra(4-N-methylpyridyl)porphine;5,10,15,20-tetrakis-(N-methyl-pyridinium-4-yl)-21H,23H-porphyrin cation;tetrakis(4-N-methylpyridyl)porphyrin;TMPYP;meso-tetrakis(N-methylpyridinium-4-yl)porphyrin;meso-Tetrakis(N-methyl-4-pyridinium)phenyl porphyrin;meso-tetrakis(1-methylpyridin-1-ium-4-yl)porphyrin;Tetrakis(4-N-methylpyridyl)porphine;meso-Tetrakis(2-N-methylpyridyl)porphine;5,10,15,20-tetrakis(1-methylpyridin-1-ium-4-yl)-21,22-dihydroporphyrin;Mesotetra(4-N-methylpyridyl)porphine;Tetrakis(N-methyl-4-pyridino)porphine;

Chemical Property of Tetrakis(4-N-methylpyridyl)porphine

Chemical Property:

• PSA: 71.82000
• LogP: 2.16420

Purity/Quality:

98.5% ^*data from raw suppliers

TETRA(4-N-METHYLPYRIDYL)PORPHINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Tetrakis(4-N-methylpyridyl)porphine

There total 4 articles about Tetrakis(4-N-methylpyridyl)porphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine (16834-13-2) + methyl iodide (74-88-4) → 5,10,15,20-tetra(N-methylpyridinium-4-yl)porphine (38673-65-3)

Guidance literature:

at 20 ℃; for 48h;

DOI:10.1016/j.ejmech.2021.113184

Reference yield:

methyl p-toluene sulfonate (80-48-8) + 5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine (16834-13-2) → 5,10,15,20-tetra(N-methylpyridinium-4-yl)porphine (38673-65-3)

Guidance literature:

In N,N-dimethyl-formamide;

DOI:10.1021/j100223a022

Reference yield:

pyridine-4-carbaldehyde (872-85-5) + pyrrole (109-97-7,30604-81-0) + methyl p-toluene sulfonate (80-48-8) → 5,10,15,20-tetra(N-methylpyridinium-4-yl)porphine (38673-65-3)

Guidance literature:

pyridine-4-carbaldehyde; pyrrole; In propionic acid; Reflux;

methyl p-toluene sulfonate;

DOI:10.3998/ark.5550190.0011.212

upstream raw materials:

methyl p-toluene sulfonate

5,10,15,20-tetra(4-pyridyl)-21H,23H-porphine

methyl iodide

pyridine-4-carbaldehyde

Refernces

• 1、 Cho, K. C.,Che, C. M.,Ng, K. M.,Choy, C. L.. "Electron Transfer between Cytochrome c and Porphyrins". . p. 2814 - 2818. Retrieved 1986.
• 2、 Guleria, Mohini,Suman, Shishu K.,Mitra, Jyotsna B.,Shelar, Sandeep B.,Amirdhanayagam, Jeyachitra,Sarma, Haladhar D.,Dash, Ashutosh,Das, Tapas. "Effect of structural variation on tumor targeting efficacy of cationically charged porphyrin derivatives: Comparative in-vitro and in-vivo evaluation for possible potential in PET and PDT". . . Retrieved 2021/02/02.
• 3、 Zhao, Ping,Liu, Min-Chao,Madanayake, Thushara W.,Reena, Chawla,Zheng, Min,Cheng, Zhen-Feng,Huang, Yu-Min,Wang, Xia-Hong. "Cationic porphyrin@SPION nanospheres as multifunctional anticancer therapeutics: Magnetic targeting, photodynamic potential and bio-safety research". . p. 103137 - 103148. Retrieved 2016/11/13.