(R)-4-allylamino-4-methoxycarbonyl-2-methylenebutyl benzoate

Base Information

• Chemical Name: (R)-4-allylamino-4-methoxycarbonyl-2-methylenebutyl benzoate
• CAS No.: 1049749-08-7
• Molecular Formula: C₁₇H₂₁NO₄
• Molecular Weight: 303.358
• Mol file: 1049749-08-7.mol

Synonyms:(R)-4-allylamino-4-methoxycarbonyl-2-methylenebutyl benzoate

Chemical Property of (R)-4-allylamino-4-methoxycarbonyl-2-methylenebutyl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (R)-4-allylamino-4-methoxycarbonyl-2-methylenebutyl benzoate

There total 1 articles about (R)-4-allylamino-4-methoxycarbonyl-2-methylenebutyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2-(chloromethyl)allyl benzoate (81694-54-4) + methyl (2R)-2-amino-4-pentenoate hydrochloride (173723-62-1,217440-34-1) → (R)-4-allylamino-4-methoxycarbonyl-2-methylenebutyl benzoate (1049749-08-7)

Guidance literature:

With tetrabutylammomium bromide; sodium carbonate; sodium iodide; In water; acetonitrile; for 14h; Heating;

DOI:10.1021/jo8008885

Reference yield: 99.0%

(R)-4-allylamino-4-methoxycarbonyl-2-methylenebutyl benzoate (1049749-08-7) + di-tert-butyl dicarbonate (24424-99-5) → C22H29NO6 (1119460-79-5)

Guidance literature:

In dichloromethane; at 20 ℃; for 16h;

DOI:10.1021/jo8008885

Reference yield: 40.0%

(R)-4-allylamino-4-methoxycarbonyl-2-methylenebutyl benzoate (1049749-08-7) + di-tert-butyl dicarbonate (24424-99-5) → methyl (R)-N-(tert-butoxycarbonyl)-5-benzoyloxymethyl-1,2,3,6-tetrahydropyridine-2-carboxylate (1049749-09-8)

Guidance literature:

(R)-4-allylamino-4-methoxycarbonyl-2-methylenebutyl benzoate; tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride;

di-tert-butyl dicarbonate; Further stages.;

DOI:10.1021/jo8008885

upstream raw materials:

2-(chloromethyl)allyl benzoate

methyl (2R)-2-amino-4-pentenoate hydrochloride

Downstream raw materials:

C₂₂H₂₉NO₆

methyl (R)-N-(tert-butoxycarbonyl)-5-benzoyloxymethyl-1,2,3,6-tetrahydropyridine-2-carboxylate