Dimethyl-phenyl-butyramide

Base Information

Chemical Name:Dimethyl-phenyl-butyramide
CAS No.:100366-87-8
Molecular Formula:C₁₂H₁₇NO
Molecular Weight:191.273
Hs Code.:
DSSTox Substance ID:DTXSID101285432

Synonyms:dimethyl-phenyl-butyramide;100366-87-8;SCHEMBL2416799;DTXSID101285432;alpha-(1,1-Dimethylethyl)benzeneacetamide

Suppliers and Price of Dimethyl-phenyl-butyramide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
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Total 0 raw suppliers

Chemical Property of Dimethyl-phenyl-butyramide

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:191.131014166
Heavy Atom Count:14
Complexity:199

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C(C1=CC=CC=C1)C(=O)N

Technology Process of Dimethyl-phenyl-butyramide

There total 4 articles about Dimethyl-phenyl-butyramide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 51631-70-0
α-Phenyl-neopentyl-carbonsaeurechlorid

: 100366-87-8
α-(tert-butyl)phenylacetamide

Guidance literature:: With ammonium hydroxide; In diethyl ether; at 0 ℃;
DOI:10.1021/jo00358a034

Reference yield:

: 938-16-9
2,2-dimethylpropiophenone

: 100366-87-8
α-(tert-butyl)phenylacetamide

Guidance literature:: Multi-step reaction with 5 steps

1: 100 percent / NaBH₄ / ethanol; methanol / 2 h

2: 72 percent / SOCl₂ / 23 °C

3: 1.) Mg, methyl iodide / 1.) THF, ether, reflux, 1 h, 2.) 0 deg C, 1 h

4: SOCl₂ / 1.5 h / Heating

5: 82 percent / concd. NH₄OH / diethyl ether / 0 °C

With ammonium hydroxide; sodium tetrahydroborate; thionyl chloride; magnesium; methyl iodide; In methanol; diethyl ether; ethanol;
DOI:10.1021/jo00358a034

Reference yield:

: 1007-26-7
(2,2-dimethyl-1-propyl)benzene

: 100366-87-8
α-(tert-butyl)phenylacetamide

Guidance literature:: Multi-step reaction with 4 steps

1: 72 percent / SOCl₂ / 23 °C

2: 1.) Mg, methyl iodide / 1.) THF, ether, reflux, 1 h, 2.) 0 deg C, 1 h

3: SOCl₂ / 1.5 h / Heating

4: 82 percent / concd. NH₄OH / diethyl ether / 0 °C

With ammonium hydroxide; thionyl chloride; magnesium; methyl iodide; In diethyl ether;
DOI:10.1021/jo00358a034