rac-N-benzyl-1-(naphth-2-yl)propan-2-amine

Base Information

• Chemical Name: rac-N-benzyl-1-(naphth-2-yl)propan-2-amine
• CAS No.: 1219495-30-3
• Molecular Formula: C₂₀H₂₁N
• Molecular Weight: 275.393
• Mol file: 1219495-30-3.mol

Synonyms:rac-N-benzyl-1-(naphth-2-yl)propan-2-amine

Chemical Property of rac-N-benzyl-1-(naphth-2-yl)propan-2-amine

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of rac-N-benzyl-1-(naphth-2-yl)propan-2-amine

There total 1 articles about rac-N-benzyl-1-(naphth-2-yl)propan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-(naphthalen-2-yl)propan-2-one (21567-68-0) + benzylamine (100-46-9) → rac-N-benzyl-1-(naphth-2-yl)propan-2-amine (1219495-30-3)

Guidance literature:

1-(naphthalen-2-yl)propan-2-one; benzylamine; With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; at 0 - 20 ℃; for 20h; Inert atmosphere;

With water; sodium hydroxide; In dichloromethane; Cooling with ice;

DOI:10.1016/j.bmc.2009.11.062

Reference yield:

rac-N-benzyl-1-(naphth-2-yl)propan-2-amine (1219495-30-3) + (R)-2-(6-methoxy-2-naphthyl)propionic acid (23979-41-1) → C14H14O3*C20H21N

Guidance literature:

In methanol; isopropyl alcohol; at 20 ℃; Resolution of racemate; Reflux;

DOI:10.1016/j.bmc.2009.11.062

upstream raw materials:

1-(naphthalen-2-yl)propan-2-one

benzylamine