N-benzyl-2-bromo-2,2-difluoro-N'-(2-((4-methoxyphenyl)ethynyl)phenyl)acetimidamide

Base Information

• Chemical Name: N-benzyl-2-bromo-2,2-difluoro-N'-(2-((4-methoxyphenyl)ethynyl)phenyl)acetimidamide
• CAS No.: 1353882-83-3
• Molecular Formula: C₂₄H₁₉BrF₂N₂O
• Molecular Weight: 469.328

Synonyms:N-benzyl-2-bromo-2,2-difluoro-N'-(2-((4-methoxyphenyl)ethynyl)phenyl)acetimidamide

Chemical Property of N-benzyl-2-bromo-2,2-difluoro-N'-(2-((4-methoxyphenyl)ethynyl)phenyl)acetimidamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzyl-2-bromo-2,2-difluoro-N'-(2-((4-methoxyphenyl)ethynyl)phenyl)acetimidamide

There total 2 articles about N-benzyl-2-bromo-2,2-difluoro-N'-(2-((4-methoxyphenyl)ethynyl)phenyl)acetimidamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C17H11BrClF2NO (1353883-61-0) + benzylamine (100-46-9) → N-benzyl-2-bromo-2,2-difluoro-N'-(2-((4-methoxyphenyl)ethynyl)phenyl)acetimidamide (1353882-83-3)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 80 ℃; for 2h;

DOI:10.1039/c1ob06528a

Reference yield:

2-((4-methoxyphenyl)ethynyl)aniline (157869-15-3) → N-benzyl-2-bromo-2,2-difluoro-N'-(2-((4-methoxyphenyl)ethynyl)phenyl)acetimidamide (1353882-83-3)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrachloromethane; triethylamine; triphenylphosphine / 80 °C

2: triethylamine / N,N-dimethyl-formamide / 2 h / 80 °C

With tetrachloromethane; triethylamine; triphenylphosphine; In N,N-dimethyl-formamide;

DOI:10.1039/c1ob06528a

Reference yield: 94.0%

N-benzyl-2-bromo-2,2-difluoro-N'-(2-((4-methoxyphenyl)ethynyl)phenyl)acetimidamide (1353882-83-3) → (Z)-N-(2-bromo-2,2-difluoro-1-(2-(4-methoxyphenyl)-1H-indol-1-yl)ethylidene)-1-phenylmethanamine (1353883-30-3)

Guidance literature:

With sodium tetrachloroaurate(III) dihyrate; In toluene; at 20 ℃; for 1h;

DOI:10.1039/c1ob06528a

upstream raw materials:

C₁₇H₁₁BrClF₂NO

benzylamine

2-((4-methoxyphenyl)ethynyl)aniline

Downstream raw materials:

(Z)-N-(2-bromo-2,2-difluoro-1-(2-(4-methoxyphenyl)-1H-indol-1-yl)ethylidene)-1-phenylmethanamine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

✦Write with AI

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1353882-83-3 N-benzyl-2-bromo-2,2-difluoro-N'-(2-((4-methoxyphenyl)ethynyl)phenyl)acetimidamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send